ArticleHeart (British Cardiac Society)2020
Association of social relationships with incident cardiovascular events and all-cause mortality.
Article in Heart (British Cardiac Society), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Social relationships and risk of cardio-cerebrovascular diseases: a meta-analysis of longitudinal cohort studies.Social psychiatry and psychiatric epidemiology · 2026Pooled it
- The impact of social isolation and loneliness on cardiovascular disease risk factors: a systematic review, meta-analysis, and bibliometric investigation.Scientific reports · 2024Pooled it
- Social isolation as a risk factor for all-cause mortality: Systematic review and meta-analysis of cohort studies.PloS one · 2023Pooled it
- Effects of Objective and Perceived Social Isolation on Cardiovascular and Brain Health: A Scientific Statement From the American Heart Association.Journal of the American Heart Association · 2022Pooled it
- The associations of code reform zoning and activity-oriented zoning with neighborhood social connectedness in the U.S., including mediation by walkability and park coverage.Health & place · 2026Article
- Applying a causal biopsychosocial model to guide medicine and psychiatry fifty years after Engel.Communications medicine · 2026Review
- Associations between migrant status, social isolation, and loneliness among older adults in India.BMC geriatrics · 2026Article
- Social environments and lifestyles linked to mortality and future health risks in metabolic syndrome: evidence from UK and US nationwide cohort studies.BMJ public health · 2026Article
- Effects of social isolation on all-cause mortality in older adults: do age, gender, and measurement matter?Innovation in aging · 2026Article
- Social integration and mortality across the life course: findings from the Tromsø study.BMC public health · 2025Article
- Prevalence of Metabolic Syndrome and Its Components in a Population in the Algerian Sahara.Ethnicity & disease · 2025Article
- Trends in cardiovascular risk factors in poland: results from the comprehensive cardiovascular risk prevention program.BMC public health · 2025Article
- The association between social determinants of health and all-cause, cardiovascular mortality in US rheumatoid arthritis: a cohort study of NHANES.BMC public health · 2025Article
- Health Inequity in the Distribution of Diseases Among Adults in the City of Pécs, Hungary, 2024.Healthcare (Basel, Switzerland) · 2025Article
- Impact of Social Determinants of Health on Cardiovascular Disease.Journal of the American Heart Association · 2025Review
- Article
- COVID-19 and stroke in women: impact on clinical, psychosocial and research aspects.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Review
- The protective effect of social support on all-cause and cardio-cerebrovascular mortality among middle-aged and older adults in the US.Scientific reports · 2024Article
- Social associations and cardiovascular mortality in the United States counties, 2016 to 2020.BMC cardiovascular disorders · 2024Article
- A wide landscape of morbidity and mortality risk associated with marital status in 0.5 million Chinese men and women: a prospective cohort study.The Lancet regional health. Western Pacific · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine how different aspects of social relationships are associated with incident cardiovascular events and all-cause mortality.
methodsIn 4139 participants from the population-based Heinz Nixdorf Recall study without previous cardiovascular disease (mean (SD) age 59.1 (7.7) years, 46.7% men), the association of self-reported instrumental, emotional and financial support and social integration at baseline with incident fatal and non-fatal cardiovascular events and all-cause mortality during 13.4-year follow-up was assessed in five different multivariable Cox proportional hazards regression models: minimally adjusted model (adjusting for age, sex, social integration or social support, respectively); biological model (minimally adjusted+systolic blood pressure, low-density and high-density lipoprotein cholesterol, glycated haemoglobin, body mass index, antihypertensive medication, lipid-lowering medication and antidiabetic medication); health behaviour model (minimally adjusted+alcohol consumption, smoking and physical activity); socioeconomic model (minimally adjusted+income, education and employment); and depression model (minimally adjusted+depression, antidepressants and anxiolytics).
results339 cardiovascular events and 530 deaths occurred during follow-up. Lack of financial support was associated with an increased cardiovascular event risk (minimally adjusted HR=1.30(95% CI 1.01 to 1.67)). Lack of social integration (social isolation) was associated with increased mortality (minimally adjusted HR=1.47 (95% CI 1.09 to 1.97)). Effect estimates did not decrease to a relevant extent in any regression model.
conclusionsPerceiving a lack of financial support is associated with a higher cardiovascular event incidence, and being socially isolated is associated with increased all-cause mortality. Future studies should investigate how persons with deficient social relationships could benefit from targeted interventions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.