ArticleNeuron2020
Context-Dependent Sensory Processing across Primary and Secondary Somatosensory Cortex.
Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Retrosplenial cortex enables context-dependent goal-directed sensorimotor transformation.eLife · 2026Article
- Contextual gating of whisker-evoked responses by frontal cortex supports flexible decision making.Nature communications · 2026Article
- Sex-specific behavioral feedback modulates sensorimotor processing and drives flexible social behavior.Nature communications · 2026Article
- Cortex-wide characterization of decision-making neural dynamics during spatial navigation.Nature communications · 2026Article
- Large cranial windows distort sensory maps and degrade feature integration in higher-order cortex.bioRxiv : the preprint server for biology · 2026Article
- Secondary Somatosensory Cortex Is Required for Learning but Not Execution of a Tactile Discrimination.The European journal of neuroscience · 2026Article
- Task demand modulates somatosensory-frontoparietal networks during delay and retrieval periods in tactile working memory.Communications biology · 2026Article
- Specialized structure of neural population codes in parietal cortex outputs.Nature neuroscience · 2025Article
- Impaired axon regeneration and heightened synaptic dynamics in the injured aged mammalian cortex.iScience · 2025Article
- Article
- Long-lasting, subtype-specific regulation of somatostatin interneurons during sensory learning.Science advances · 2025Article
- Learning, prediction accuracy, and neural plasticity in sensory cortex.Current opinion in neurobiology · 2025Review
- Pre-stimulus beta power mediates explicit and implicit perceptual biases in distinct cortical areas.Communications psychology · 2025Article
- Multimodal Correspondence between Optogenetic fMRI, Electrophysiology, and Anatomical Maps of the Secondary Somatosensory Cortex in Nonhuman Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Intra-somatosensory cortical circuits mediating pain-induced analgesia.Nature communications · 2025Article
- Neocortical somatostatin neuron diversity in cognition and learning.Trends in neurosciences · 2025Review
- Transcriptional determinants of goal-directed learning and representational drift in the parahippocampal cortex.Cell reports · 2025Article
- Perirhinal cortex learns a predictive map of the task environment.Nature communications · 2024Article
- Computational role of structure in neural activity and connectivity.Trends in cognitive sciences · 2024Review
- Article
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7 authors.
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Abstract
To interpret the environment, our brain must evaluate external stimuli against internal representations from past experiences. How primary (S1) and secondary (S2) somatosensory cortices process stimuli depending on recent experiences is unclear. Using simultaneous multi-area population imaging of projection neurons and focal optogenetic inactivation, we studied mice performing a whisker-based working memory task. We find that activity reflecting a current stimulus, the recollection of a previous stimulus (cued recall), and the stimulus category are distributed across S1 and S2. Despite this overlapping representation, S2 is important for processing cued recall responses and transmitting these responses to S1. S2 network properties differ from S1, wherein S2 persistently encodes cued recall and the stimulus category under passive conditions. Although both areas encode the stimulus category, only information in S1 is important for task performance through pathways that do not necessarily include S2. These findings reveal both distributed and segregated roles for S1 and S2 in context-dependent sensory processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.