Evidence map›Paper›PMID 32164839›Full record

ArticleCell host & microbe2020

An M. tuberculosis Metabolic Enzyme Moonlights as an Anti-Inflammatory Effector Protein.

Tina Truong, Bennett H Penn

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. mSystems · 2026
    Article
  2. Functional Analysis of Genes inIndian journal of microbiology · 2024
    Review
  3. Review
  4. Frontiers in immunology · 2021
    Article
  5. Host Cell Targets of Released Lipid and Secreted Protein Effectors ofFrontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tina TruongDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis Health, Sacramento, CA, USA; Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA, USA.
Bennett H PennDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis Health, Sacramento, CA, USA; Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA, USA. Electronic address: bhpenn@ucdavis.edu.
University of California Davis Medical Center · US

Funding

UC Davis MCB T32 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) MentorshipT32GM007377 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEDIN, FREDERIC LOUIS · 1985 to 2023
$9.9M
Understanding How the Ubiquitin Ligase CBL Regulates Innate Immune ResponsesR01AI144149 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PENN, BENNETT · 2019 to 2023
$2.4M
NIAID NIH HHS R01 AI144149
6 · The paper itself

Abstract

The mechanisms by which Mycobacterium tuberculosis evades host immunity remain enigmatic. In a recent study in the journal Nature, Wang et al. report that an enzyme acting in the bacterial cytoplasm to degrade lipids also acts as an effector protein in the host cell cytoplasm to suppress inflammation.

Indexed as

Mycobacterium tuberculosisTuberculosisAnti-Inflammatory AgentsCytokinesHumansUbiquitinationAnti-Inflammatory AgentsCytokines

Identifiers

PMID32164839
OpenAlexW3011257328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.