ArticleActa veterinaria Scandinavica2020
A comparison of respiratory function in pigs anaesthetised by propofol or alfaxalone in combination with dexmedetomidine and ketamine.
Article in Acta veterinaria Scandinavica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Pig Sedation and Anesthesia for Medical Research.Animals : an open access journal from MDPI · 2023Review
- Article
- Long duration anaesthesia in pigs with an infusion of alfaxalone and dexmedetomidine.Veterinary medicine and science · 2022Article
- Article
- Effect of 'combing' on intramuscular sedation in pigs in a clinical setting-A randomised trial.The Veterinary recordArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGeneral anaesthesia in pigs maintained with intravenous drugs such as propofol may cause respiratory depression. Alfaxalone gives less respiratory depression than propofol in some species. The aim of the investigation was to compare respiratory effects of propofol-ketamine-dexmedetomidine and alfaxalone-ketamine-dexmedetomidine in pigs. Sixteen pigs premedicated with ketamine 15 mg/kg and midazolam 1 mg/kg intramuscularly were anaesthetised with propofol or alfaxalone to allow endotracheal intubation, followed by propofol 8 mg/kg/h or alfaxalone 5 mg/kg/h in combination with ketamine 5 mg/kg/h and dexmedetomidine 4 µg/kg/h given as a continuous infusion for 60 min. The pigs breathed spontaneously with an FIO
resultsAlfaxalone treated pigs had significantly higher respiratory rates and lower PE'CO
conclusionsNo major differences in respiratory variables were found when comparing treatments. Respiratory supportive measures must be available when using both protocols.
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