Evidence map›Paper›PMID 32164688›Full record

ArticleJournal of orthopaedic surgery and research2020

The time-dependent effects of bipolar radiofrequency energy on bovine articular cartilage.

Liangquan Peng, Yusheng Li, Kai Zhang, Qi Chen, Lulu Xiao, Yiyun Geng, Yong Huang, Weimin Zhu, Wei Lu, Greg Zhang and 2 more

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. The temperature profile in elbow arthroscopy using radiofrequency ablation.Archives of orthopaedic and trauma surgery · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Liangquan PengDepartment of Sports Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China.
Yusheng LiDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Kai ZhangDepartment of Sports Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China.
Qi ChenDepartment of Sports Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China.
Lulu XiaoDepartment of Sports Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China.
Yiyun GengShenzhen Key Laboratory of Tissue Engineering, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China.
Yong HuangShenzhen Key Laboratory of Tissue Engineering, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China.
Weimin ZhuDepartment of Sports Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China.
Wei LuDepartment of Sports Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China.
Greg ZhangMcGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Zhenhan DengDepartment of Sports Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China. dengzhenhan@email.szu.edu.cn.
Daping WangDepartment of Sports Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China. dapingwang1963@qq.com.

Funding

National Natural Science Foundation of China 81672234National Natural Science Foundation of China 81902303National Natural Science Foundation of China 81902558Science and Technology Planning Project of Shenzhen Municipality 201606018Science and Technology Planning Project of Shenzhen Municipality GJHZ20180416164801042Science and Technology Planning Project of Shenzhen Municipality JCYJ20180305124912336
6 · The paper itself

Abstract

purposeThe purpose of this study was to compare the effect of bipolar radiofrequency energy (bRFE) on chondroplasty at the different time durations in an in vitro experiment that simulated an arthroscopic procedure.

methodsSix fresh bovine knees were used in our study. Six squares were marked on both the medical and lateral femoral condyles of each femur. Each square was respectively treated with bRFE for 0 s, 10 s, 20 s, 30 s, 40 s and 50 s. Full-thickness articular cartilage specimens were harvested from the treatment areas. Each specimen was divided into three distinct parts: one for hematoxylin/eosin staining histology, another for cartilage surface contouring assessment via scanning electron microscopy (SEM), and the last one for glycosaminoglycan (GAG) content measurement.

resultsbRFE caused time-correlated damage to chondrocytes, and GAG content in the cartilage was negatively correlated to exposure time. bRFE caused time-correlated damage to chondrocytes. The GAG content in the cartilage negatively correlated with the exposure time. The sealing effect positively correlated with the exposure time. Additionally, it took at least 20 s of radiofrequency exposure to render a smooth cartilage surface and a score of 2 (normal) in the scoring system used.

conclusionbRFE usage in chondroplasty could effectively trim and polish the cartilage lesion area; however, it induces a dose-dependent detrimental effect on chondrocytes and metabolic activity that negatively correlated with the treatment time. Therefore, cautions should be taken in the use of bRFE for treatment of articular cartilage injury.

Indexed as

AnimalsCartilage, ArticularCattleCell SurvivalRadiofrequency AblationTime FactorsArticular cartilageChondrocyteChondroplastyRadiofrequency energyScanning electron microscope

Identifiers

PMID32164688
PMCPMC7069051

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.