Evidence map›Paper›PMID 32164606›Full record

ArticleBMC pregnancy and childbirth2020

Intergenerational transmission of health disparities among Turkish-origin immigrants in Germany: study protocol of a multi-centric cohort study (BaBi-stress and BaBeK study).

Jacob Spallek, Laura Scholaske, Medlin Kurt, Denise Lindner-Matthes, Sonja Entringer

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. [Life course epidemiology in migrant health research].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jacob SpallekDepartment of Public Health, Brandenburg University of Technology, Universitätsplatz 1, 01968, Senftenberg, Germany. jacob.spallek@b-tu.de.ORCID http://orcid.org/0000-0001-6312-034X
Laura ScholaskeCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Institute for Medical Psychology, Luisenstr. 57, Berlin, 10117, Germany.
Medlin KurtDepartment of Public Health, Brandenburg University of Technology, Universitätsplatz 1, 01968, Senftenberg, Germany.
Denise Lindner-MatthesDepartment of Public Health, Brandenburg University of Technology, Universitätsplatz 1, 01968, Senftenberg, Germany.
Sonja EntringerCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Institute for Medical Psychology, Luisenstr. 57, Berlin, 10117, Germany.
Brandenburg University of Technology Cottbus-Senftenberg · DEBielefeld University · DEHumboldt-Universität zu Berlin · DEUniversity of California, Irvine · US

Funding

Deutsche Forschungsgemeinschaft (DFG) SP 1495/3-1
6 · The paper itself

Abstract

backgroundImmigrants in Germany exhibit higher levels of social disadvantage when compared to the non-immigrated population. Turkish-origin immigrants constitute an important immigrant group in Germany and show disparities in some health domains that are evident from birth onwards. Several studies have shown the mechanisms by which social disadvantage is biologically embedded to affect health over the lifespan. Relatively little, however, is still known about if and how the maternal social situation is transmitted to the next generation. This study therefore aims to analyse the effects of maternal socioeconomic status and migration status on stress-related maternal-placental-fetal (MPF) biological processes during pregnancy on infant birth and health outcomes.

methodsThis longitudinal cohort study of N = 144 child-mother dyads is located at two study sites in Germany and includes pregnant women of Turkish origin living in Germany as well as pregnant German women. During pregnancy, MPF stress biology markers from maternal blood and saliva samples, maternal socio-economic and migration-related information, medical risk variables and psychological well-being are assessed. After birth, infant anthropometric measures and developmental outcomes are assessed. The same measures will be assessed in and compared to Turkish pregnant women based on a collaboration with BABIP study in Istanbul. DISCUSSION: This is the first study on intergenerational transmission of health disparities in Germany with a focus on women of Turkish-origin. The study faces similar risks of bias as other birth cohorts do. The study has implemented various measures, e.g. culturally sensitive recruitment strategies, attempt to recruit and follow-up as many pregnant women as possible independent of their social or cultural background. Nevertheless, the response rate among lower-educated families is lower. The possibility to compare results with a cohort from Turkey is a strength of this study. However, starting at different times and with slightly different recruitment strategies and designs may result in cohort effects and may affect comparability of the sub-cohorts.

trial registrationN.A. (Observational study, no clinical trial, no interventions on human participants).

Indexed as

Emigrants and ImmigrantsFetal DevelopmentStress, PhysiologicalFemaleGermanyHealthcare DisparitiesHumansLongitudinal StudiesMulticenter Studies as TopicObservational Studies as TopicPlacentaPregnancyPrenatal Exposure Delayed EffectsResearch DesignSocial ClassTurkeyPregnancy and birthStress biologyTransmission of health inequalitiesTurkish immigrants

Identifiers

PMID32164606
PMCPMC7069210
OpenAlexW3010899287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.