Evidence map›Paper›PMID 32164562›Full record

ArticleBMC infectious diseases2020

Temporal decline in diarrhea episodes and mortality in Kiribati children two years following rotavirus vaccine introduction, despite high malnutrition rates: a retrospective review.

Jana Lai, Cattram Nguyen, Beia Tabwaia, Agnes Nikuata, Nikarawa Baueri, Eretii Timeon, Mohammed Diaaldeen, Tinai Iuta, Murat Hakan Ozturk, Aaron Moore and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Welcome evidence of vaccine impact in the Pacific.The Lancet regional health. Western Pacific · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 5 countries.

Jana LaiMurdoch Children's Research Institute, Melbourne, Australia. jana.yr.lai@gmail.com.ORCID http://orcid.org/0000-0003-3067-5829
Cattram NguyenMurdoch Children's Research Institute, Melbourne, Australia.
Beia TabwaiaMinistry of Health and Medical Services, Tarawa, Kiribati.
Agnes NikuataWorld Health Organization, Tarawa, Kiribati.
Nikarawa BaueriMinistry of Health and Medical Services, Tarawa, Kiribati.
Eretii TimeonMinistry of Health and Medical Services, Tarawa, Kiribati.
Mohammed DiaaldeenUNICEF, Tarawa, Kiribati.
Tinai IutaUNICEF, Tarawa, Kiribati.
Murat Hakan OzturkUNICEF Pacific, Suva, Fiji.
Aaron MooreUNICEF Australia, Sydney, Australia.
Alice HallUNICEF Australia, Sydney, Australia.
Batmunkh NyambatWHO Regional Office for the Western Pacific, Manila, Philippines.
Stephanie DavisAustralian National University, Canberra, Australia.
Ataur RahmanUNICEF Pacific, Suva, Fiji.
Wendy ErasmusUNICEF Pacific, Suva, Fiji.
Kimberley FoxWHO Regional Office for the Western Pacific, Manila, Philippines.
Fiona RussellMurdoch Children's Research Institute, Melbourne, Australia.
Ministry of Fisheries and Marine Resource Development · KIUniversity of the South Pacific · FJAustralian National University · AUThe University of Melbourne · AUCenters for Disease Control and Prevention · USWorld Health Organization Regional Office for the Western Pacific · PH

Funding

WHO Regional Office for the Western Pacific 00000World Health Organization 001
6 · The paper itself

Abstract

backgroundKiribati introduced rotavirus vaccine in 2015. To estimate the impact of rotavirus vaccine on acute gastroenteritis (AGE) and severe acute malnutrition (SAM) among children under 5 in Kiribati, a retrospective review of inpatient and outpatient AGE and hospitalized SAM was undertaken.

methodsInpatient data for admissions and hospital deaths due to AGE, SAM and all-causes were collected for children under 5 from all hospitals on the main island, Tarawa, from January 2010-December 2013 (pre-rotavirus vaccine) and January 2016-September 2017 (post-rotavirus vaccine). National outpatient diarrhea data were collected from January 2010 to August 2017 for under 5. An interrupted time-series analysis was undertaken to estimate the effect of rotavirus vaccine on the rates of inpatient and outpatient AGE, inpatient SAM; and inpatient case fatality rates for AGE and SAM, were calculated pre- and post-rotavirus vaccine introduction.

resultsThe incidence rate of AGE admissions from Tarawa and national AGE outpatient presentations significantly declined by 37 and 44%, respectively, 2 years following rotavirus vaccine introduction. There was a significant decline in the percentage of AGE contributing to all-cause under 5 admissions (12·8% vs. 7·2%, p < 0·001) and all-cause under-five mortality (15·9% vs. 5·7%, p = 0·006) pre- and post-rotavirus vaccine introduction. The estimated incidence rate of inpatient SAM decreased by 24% in under 5 s, 2 years following rotavirus vaccine introduction.

conclusionsAGE morbidity and mortality and hospitalized SAM rates have declined following rotavirus vaccine introduction in Kiribati children.

Indexed as

Child, PreschoolDiarrheaFecesFemaleGastroenteritisHospitalsHumansInfantInterrupted Time Series AnalysisMaleMicronesiaMorbidityRetrospective StudiesRotavirus InfectionsRotavirus VaccinesSevere Acute MalnutritionRotavirus VaccinesDiarrheal diseaseHospitalKiribatiRotavirus vaccineSevere acute malnutrition

Identifiers

PMID32164562
PMCPMC7069014
OpenAlexW3011083271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.