Evidence map›Paper›PMID 32164537›Full record

ArticleBMC cardiovascular disorders2020

Assessing left ventricular systolic function in children with a history of Kawasaki disease.

Zhou Lin, Jingjing Zheng, Weiling Chen, Tingting Ding, Wei Yu, Bei Xia

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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  14. Kawasaki Disease and Allergic Diseases.Frontiers in pediatrics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhou LinDepartment of Ultrasound, Shenzhen Children's Hospital, Shenzhen, China.
Jingjing ZhengDepartment of Ultrasound, Shenzhen Children's Hospital, Shenzhen, China.
Weiling ChenDepartment of Ultrasound, Shenzhen Children's Hospital, Shenzhen, China.
Tingting DingDepartment of Ultrasound, Shenzhen Children's Hospital, Shenzhen, China.
Wei YuDepartment of Ultrasound, Shenzhen Children's Hospital, Shenzhen, China.
Bei XiaDepartment of Ultrasound, Shenzhen Children's Hospital, Shenzhen, China. xiabeimd@163.com.
Shenzhen Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of Kawasaki disease (KD) is increasing. Indeed, KD has become the most common cause of acquired heart disease in children. Previous studies have well summarized the acute phase left ventricular (LV) systolic dysfunction using speckle tracking echocardiography (STE); however, changes in LV systolic function after long-term follow-up remain unclear.

methodsOne hundred children with a history of KD, but without coronary artery aneurysms, were enrolled. These children were divided into two subgroups based on the presence or absence of coronary artery dilatation (CAD). The duration of follow-up was > 7 years. The control group consisted of 51 healthy children. The LV myocardial strain were measured by two- and three-dimensional STE.

resultsTwo-dimensional STE not only revealed that LV longitudinal strain decreased in part of segments in both KD groups, but also showed that global strain decreased in the KD group with CAD compared to the controls (P < 0.05). Global longitudinal strain (GLS), global circumferential strain (GCS), global radial strain (GRS), and global area strain (GAS) were obtained by 3D STE. Compared to the controls, GLS and GAS decreased in both KD groups (P < 0.05). GCS and GRS decreased in the KD group with CAD, but was unchanged in the KD group without CAD (P < 0.05).

conclusionsLV systolic dysfunction in children with KD and CAD was more severe than KD children without CAD compared to healthy children. This dysfunction can be assessed by LV regional and global myocardial strain using two- and three-dimensional STE.

Indexed as

Echocardiography, DopplerVentricular Function, LeftAdolescentAge FactorsCase-Control StudiesChildCoronary AneurysmFemaleHumansMaleMucocutaneous Lymph Node SyndromePredictive Value of TestsPrognosisRisk FactorsSeverity of Illness IndexSystoleFollow-upKawasaki diseaseLong-termSpeckle tacking echocardiography

Identifiers

PMID32164537
PMCPMC7068877
OpenAlexW3012306055

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.