Evidence map›Paper›PMID 32164459›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Synthesis, biological evaluation and molecular modelling of 2,4-disubstituted-5-(6-alkylpyridin-2-yl)-1

Myoung-Soon Park, Hyun-Ju Park, Young Jae An, Joon Hun Choi, Geunyoung Cha, Hwa Jeong Lee, So-Jung Park, Purushottam M Dewang, Dae-Kee Kim

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Myoung-Soon ParkGraduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, South Korea.
Hyun-Ju ParkSchool of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
Young Jae AnGraduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, South Korea.
Joon Hun ChoiGraduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, South Korea.
Geunyoung ChaGraduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, South Korea.
Hwa Jeong LeeGraduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, South Korea.
So-Jung ParkSchool of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
Purushottam M DewangGraduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, South Korea.
Dae-Kee KimGraduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 2,4-disubstituted-5-(6-alkylpyridin-2-yl)-1

Indexed as

Caco-2 CellsCell LineDose-Response Relationship, DrugHumansImidazolesModels, MolecularMolecular StructureProtein Kinase InhibitorsReceptor, Transforming Growth Factor-beta Type IStructure-Activity RelationshipImidazolesProtein Kinase InhibitorsReceptor, Transforming Growth Factor-beta Type ITGFBR1 protein, human2,4-Disubstituted-5-(6-alkylpyridin-2-yl)-1H-imidazolesALK5 inhibitioncancer immunotherapeutic agentdocking

Identifiers

PMID32164459
PMCPMC7144182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.