Evidence map›Paper›PMID 32164354›Full record

ArticleCancers2020

High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma.

Martin F Orth, Tilman L B Hölting, Marlene Dallmayer, Fabienne S Wehweck, Tanja Paul, Julian Musa, Michaela C Baldauf, Didier Surdez, Olivier Delattre, Maximilian M L Knott and 17 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 10 institutions in 4 countries.

Martin F OrthMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Tilman L B HöltingMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Marlene DallmayerMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Fabienne S WehweckMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Tanja PaulMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Julian MusaMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Michaela C BaldaufMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Didier SurdezINSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, 75248 Paris, France.
Olivier DelattreINSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, 75248 Paris, France.
Maximilian M L KnottMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Laura Romero-PérezMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Merve KasanMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Florencia Cidre-AranazMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Julia S GerkeMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Shunya OhmuraMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Jing LiMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Aruna MarchettoMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Anton G HenssenDepartment of Pediatric Hematology/Oncology/BMT, Charité-University Medicine Berlin, 13353 Berlin, Germany.
Özlem ÖzenDepartment of Pathology, Başkent University Hospital, 06490 Ankara, Turkey.
Shintaro SugitaDepartment of Surgical Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Tadashi HasegawaDepartment of Surgical Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Takayuki KanasekiDepartment of Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Stefanie BertramInstitute of Pathology, University Hospital Essen, 45147 Essen, Germany.
Uta DirksenPediatrics III, AYA Unit, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Wolfgang HartmannDivision of Translational Oncology, Gerhard-Domagk-Institute for Pathology, University Hospital Münster, 48149 Münster, Germany.
Thomas KirchnerInstitute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Thomas G P GrünewaldMax-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Ludwig-Maximilians-Universität München · DELMU Klinikum · DESapporo Medical University · JPEssen University Hospital · DEGerman Cancer Research Center · DEInserm · FRUniversity Hospital Münster · DEBaşkent University Hospital · TRCharité - Universitätsmedizin Berlin · DEHeidelberg University · DE

Funding

Deutsche Forschungsgemeinschaft DFG 391665916Deutsche Krebshilfe DKH-70112257
6 · The paper itself

Abstract

Ewing sarcoma (EwS) is an aggressive cancer displaying an undifferentiated small-round-cell histomorphology that can be easily confused with a broad spectrum of differential diagnoses. Using comparative transcriptomics and immunohistochemistry (IHC), we previously identified BCL11B and GLG1 as potential specific auxiliary IHC markers for

Indexed as

BCL11BbiomarkersdiagnosticsEwing sarcomaGLG1immunohistochemistry

Identifiers

PMID32164354
PMCPMC7139395
OpenAlexW3012142761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.