Evidence map›Paper›PMID 32164338›Full record

ArticlePathogens (Basel, Switzerland)2020

Improved Metagenomic Taxonomic Profiling Using a Curated Core Gene-Based Bacterial Database Reveals Unrecognized Species in the Genus

Mauricio Chalita, Sung-Min Ha, Yeong Ouk Kim, Hyun-Seok Oh, Seok-Hwan Yoon, Jongsik Chun

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. RNA sequencing analysis of viromes ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. EzBioCloud: a genome-driven database and platform for microbiome identification and discovery.International journal of systematic and evolutionary microbiology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Taxonomic composition and variation in the gut microbiota of laboratory mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2021
    Review
  14. Metagenomic Association Analysis of Gut SymbiontFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mauricio ChalitaInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.
Sung-Min HaChunLab Inc., Seoul 06725, Korea.
Yeong Ouk KimInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.
Hyun-Seok OhInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.
Seok-Hwan YoonChunLab Inc., Seoul 06725, Korea.
Jongsik ChunInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.ORCID 0000-0003-3385-5171
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shotgun metagenomics is of great importance in order to understand the composition of the microbial community associated with a sample and the potential impact it may exert on its host. For clinical metagenomics, one of the initial challenges is the accurate identification of a pathogen of interest and ability to single out that pathogen within a complex community of microorganisms. However, in absence of an accurate identification of those microorganisms, any kind of conclusion or diagnosis based on misidentification may lead to erroneous conclusions, especially when comparing distinct groups of individuals. When comparing a shotgun metagenomic sample against a reference genome sequence database, the classification itself is dependent on the contents of the database. Focusing on the genus

Indexed as

genomospeciesshotgun metagenomicsStreptococcustaxonomy prediction

Identifiers

PMID32164338
PMCPMC7157611
OpenAlexW3012214338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.