Evidence map›Paper›PMID 32164244›Full record

ReviewJournal of clinical medicine2020

Therapeutic Applications of Curcumin Nanomedicine Formulations in Cardiovascular Diseases.

Bahare Salehi, María L Del Prado-Audelo, Hernán Cortés, Gerardo Leyva-Gómez, Zorica Stojanović-Radić, Yengkhom Disco Singh, Jayanta Kumar Patra, Gitishree Das, Natália Martins, Miquel Martorell and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 86 citations in OpenAlex.

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  9. Current State of Scientific Knowledge on Curcumin Encapsulation and Applications.Recent advances in food, nutrition & agriculture · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 8 countries.

Bahare SalehiStudent Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran.ORCID 0000-0002-6900-9797
María L Del Prado-AudeloDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Circuito Exterior S/N, Del. Coyoacán, Mexico City 04510, Mexico.ORCID 0000-0003-4238-2724
Hernán CortésLaboratorio de Medicina Genómica, Departamento de Genética, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.ORCID 0000-0002-6147-4109
Gerardo Leyva-GómezDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Circuito Exterior S/N, Del. Coyoacán, Mexico City 04510, Mexico.ORCID 0000-0002-7940-1100
Zorica Stojanović-RadićDepartment of Biology and Ecology, Faculty of Science and Mathematics, University of Niš, 18000 Niš, Serbia.
Yengkhom Disco SinghDepartment of Post-Harvest Technology, College of Horticulture and Forestry, Central Agricultural University, Pasighat-791102, Arunachal Pradesh, India.ORCID 0000-0002-7580-2345
Jayanta Kumar PatraResearch Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, Goyangsi-10326, Korea.
Gitishree DasResearch Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, Goyangsi-10326, Korea.
Natália MartinsFaculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Miquel MartorellDepartment of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepcion 4070386, Chile.ORCID 0000-0003-3183-7623
Marzieh Sharifi-RadResearch Department of Agronomy and Plant Breeding, Agricultural Research Institute, University of Zabol, Zabol 3585698613, Iran.
William C ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong, China.
Javad Sharifi-RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran.ORCID 0000-0002-7301-8151
Dongguk University · KRBam University of Medical Sciences · IRCentral Agricultural University · INInstituto Nacional de Rehabilitación · MXQueen Elizabeth Hospital · CNShahid Beheshti University of Medical Sciences · IRUniversidad de Cuautitlán Izcalli · MXUniversidade do Porto · PTUniversidad Nacional Autónoma de México · MXUniversity of Concepción · CLUniversity of Nis · RSZabol University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVD) compromises a group of heart and blood vessels disorders with high impact on human health and wellbeing. Curcumin (CUR) have demonstrated beneficial effects on these group of diseases that represent a global burden with a prevalence that continues increasing progressively. Pre- and clinical studies have demonstrated the CUR effects in CVD through its anti-hypercholesterolemic and anti-atherosclerotic effects and its protective properties against cardiac ischemia and reperfusion. However, the CUR therapeutic limitation is its bioavailability. New CUR nanomedicine formulations are developed to solve this problem. The present article aims to discuss different studies and approaches looking into the promising role of nanotechnology-based drug delivery systems to deliver CUR and its derivatives in CVD treatment, with an emphasis on their formulation properties, experimental evidence, bioactivity, as well as challenges and opportunities in developing these systems.

Indexed as

cardiovascular diseasecurcuminliposomenanocurcuminnanoformulationnanomedicine

Identifiers

PMID32164244
PMCPMC7141226
OpenAlexW3011530534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.