Evidence map›Paper›PMID 32163221›Full record

ArticleHuman brain mapping2020

A toolbox for brain network construction and classification (BrainNetClass).

Zhen Zhou, Xiaobo Chen, Yu Zhang, Dan Hu, Lishan Qiao, Renping Yu, Pew-Thian Yap, Gang Pan, Han Zhang, Dinggang Shen

Abstract read
In one paragraph

Article in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhen ZhouCollege of Computer Science and Technology, Zhejiang University, Hangzhou, China.ORCID 0000-0002-9169-5885
Xiaobo ChenDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0001-9940-1637
Yu ZhangDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Dan HuDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lishan QiaoDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Renping YuDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Pew-Thian YapDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Gang PanCollege of Computer Science and Technology, Zhejiang University, Hangzhou, China.
Han ZhangDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-6645-8810
Dinggang ShenDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

Prospective study of the onset of schizophreniaP50MH064065 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILMORE, JOHN HORACE · 2002 to 2011
$19.6M
Quantifying Brain Abnormality by Multimodality Neuroimage Analysis,R01AG041721 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, MINGXIA · 2012 to 2019
$3.0M
Assessing Large-scale Brain Connectivities in Mild Cognitive ImpairmentR01AG042599 · NIA · UNIVERSITY OF GEORGIA · PI LIU, TIANMING · 2013 to 2017
$1.4M
Diagnosis of Alzheimer's Disease Using Dynamic High-Order Brain NetworksR01EB022880 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
NIA NIH HHS R01 AG041721NIA NIH HHS R01 AG042599NIBIB NIH HHS R01 EB022880NIH HHS AG041721NIH HHS AG042599NIH HHS EB022880NIMH NIH HHS P50 MH064065
6 · The paper itself

Abstract

Brain functional network has been increasingly used in understanding brain functions and diseases. While many network construction methods have been proposed, the progress in the field still largely relies on static pairwise Pearson's correlation-based functional network and group-level comparisons. We introduce a "Brain Network Construction and Classification (BrainNetClass)" toolbox to promote more advanced brain network construction methods to the filed, including some state-of-the-art methods that were recently developed to capture complex and high-order interactions among brain regions. The toolbox also integrates a well-accepted and rigorous classification framework based on brain connectome features toward individualized disease diagnosis in a hope that the advanced network modeling could boost the subsequent classification. BrainNetClass is a MATLAB-based, open-source, cross-platform toolbox with both graphical user-friendly interfaces and a command line mode targeting cognitive neuroscientists and clinicians for promoting reliability, reproducibility, and interpretability of connectome-based, computer-aided diagnosis. It generates abundant classification-related results from network presentations to contributing features that have been largely ignored by most studies to grant users the ability of evaluating the disease diagnostic model and its robustness and generalizability. We demonstrate the effectiveness of the toolbox on real resting-state functional MRI datasets. BrainNetClass (v1.0) is available at https://github.com/zzstefan/BrainNetClass.

Indexed as

BrainNerve NetConnectomeHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingSoftwarebrain connectomedynamic functional connectivityfunctional connectivitymachine learningpredictionsparse representationtoolbox

Identifiers

PMID32163221
PMCPMC7294070

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.