Evidence map›Paper›PMID 32162838›Full record

ArticleArthritis & rheumatology (Hoboken, N.J.)2020

Elective Termination of Pregnancy in Autoimmune Rheumatic Diseases: Experience From Two Databases.

Michael D Lockshin, Marta Guerra, Jane E Salmon

Open access · greenAbstract read
In one paragraph

Article in Arthritis & rheumatology (Hoboken, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Family Planning and Rheumatoid Arthritis.Current rheumatology reports · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael D LockshinHospital for Special Surgery and Weill Cornell Medicine, New York, New York.ORCID 0000-0003-1034-0351
Marta GuerraHospital for Special Surgery and Weill Cornell Medicine, New York, New York.
Jane E SalmonHospital for Special Surgery and Weill Cornell Medicine, New York, New York.ORCID 0000-0001-9113-7122
Hospital for Special Surgery · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Predictors of Pregnancy Outcome In SLE and APSR01AR049772 · NIAMS · HOSPITAL FOR SPECIAL SURGERY · PI SALMON, JANE E · 2003 to 2012
$12.6M
Cognitive dysfunction in neuropsychiatric-SLER55AR049165 · NIAMS · HOSPITAL FOR SPECIAL SURGERY · PI LOCKSHIN, MICHAEL D · 2002 to 2002
$100k
15th International Congress on Antiphospholipid AntibodiesR13HL129715 · NHLBI · HOSPITAL FOR SPECIAL SURGERY · PI ERKAN, DORUK, LOCKSHIN, MICHAEL D · 2016 to 2016
$5k
NCATS NIH HHS UL1 TR002384NHLBI NIH HHS R13 HL129715NIAMS NIH HHS R01 AR049772NIAMS NIH HHS R55 AR049165
6 · The paper itself

Abstract

objectiveTo provide reference data regarding the frequency and safety of elective termination of pregnancy in women with autoimmune rheumatic diseases followed up in 2 referral databases.

methodsTwo large databases, one from an autoimmune rheumatic disease referral clinical practice with a known interest in pregnancy (the Barbara Volcker Center for Women and Rheumatic Disease [BVC]), and one from an observational study of systemic lupus erythematosus- and antiphospholipid antibody-associated pregnancies (Predictors of Pregnancy Outcome: Biomarkers in Antiphospholipid Antibody Syndrome and Systemic Lupus Erythematosus [PROMISSE]), were interrogated for histories of prior elective termination of pregnancy and complications related to incident pregnancy termination.

resultsOf women who had had prior pregnancies, 21.7% of 1,307 in the BVC database and 25.3% of 297 in the PROMISSE database gave histories of 1-5 prior elective terminations of pregnancy; BVC patients reported no flares or hospitalizable complications due to pregnancy termination. Of 674 incident pregnancies, termination for fetal or maternal reasons was recommended for 15 (2%); of these, 2 fetuses died before the procedure was carried out and 1 woman declined termination and, though gravely ill, successfully delivered. She died of cardiomyopathy 3 years later.

conclusionMany patients with autoimmune rheumatic disease undergo elective termination of pregnancy; few report complications. In medically indicated termination of pregnancy, there are no adverse signals of unusual complications or disease flare.

Indexed as

Abortion, InducedAdultAutoimmune DiseasesDatabases, FactualFemaleHumansMiddle AgedPregnancyPregnancy ComplicationsRheumatic Diseases

Identifiers

PMID32162838
PMCPMC7486237
OpenAlexW3012076543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.