Evidence map›Paper›PMID 32162485›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2020

Image-guided tumor surgery: The emerging role of nanotechnology.

Nicholas E Wojtynek, Aaron M Mohs

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicholas E WojtynekEppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska.ORCID 0000-0001-7375-2711
Aaron M MohsFred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska.ORCID 0000-0002-9353-5404
Nebraska Medical Center · US

Funding

Hyaluronic Acid Based Nanoparticles for Targeted Image-Guided Tumor SurgeryR01EB019449 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MOHS, AARON M. · 2014 to 2017
$1.3M
Tunable Fluorescent Organic Nanoparticles for Cancer Imaging ApplicationsR21CA212500 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI MOHS, AARON M. · 2017 to 2019
$596k
NCI NIH HHS R21 CA212500NIBIB NIH HHS R01 EB019449
6 · The paper itself

Abstract

Surgical resection is a mainstay treatment for solid tumors. Yet, methods to distinguish malignant from healthy tissue are primarily limited to tactile and visual cues as well as the surgeon's experience. As a result, there is a possibility that a positive surgical margin (PSM) or the presence of residual tumor left behind after resection may occur. It is well-documented that PSMs can negatively impact treatment outcomes and survival, as well as pose an economic burden. Therefore, surgical tumor imaging techniques have emerged as a promising method to decrease PSM rates. Nanoparticles (NPs) have unique characteristics to serve as optical contrast agents during image-guided surgery (IGS). Recently, there has been tremendous growth in the volume and types of NPs used for IGS, including clinical trials. Herein, we describe the most recent contributions of nanotechnology for surgical tumor identification. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease Implantable Materials and Surgical Technologies > Nanoscale Tools and Techniques in Surgery Diagnostic Tools > in vivo Nanodiagnostics and Imaging.

Indexed as

NanotechnologySurgery, Computer-AssistedAnimalsHumansNanomedicineNanoparticlesNeoplasmsPhotoacoustic Techniquesfluorescence-guided surgeryimage-guided surgeryimagingnanoparticleopticalsurgical oncology

Identifiers

PMID32162485
PMCPMC9469762
OpenAlexW3012144997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.