Evidence map›Paper›PMID 32162434›Full record

ArticleThe American journal on addictions2020

Buprenorphine Treatment for Opioid Use Disorder in Community-Based Settings: Outcome Related to Intensity of Services and Urine Drug Test Results.

Marc Galanter, John Femino, Brooke Hunter, Mary Hauser

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in The American journal on addictions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05594121 (A Pragmatic, Multi-centre, Open-label, Randomized, 12-month, Parallel Group, Superiority Study to Compare the Effectiveness of Subcutaneous Buprenorphine Depot), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05594121 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

A Pragmatic, Multi-centre, Open-label, Randomized, 12-month, Parallel Group, Superiority Study to Compare the Effectiveness of Subcutaneous Buprenorphine Depot (Sublocade®) vs Daily Sublingual Buprenorphine With Naloxone (Suboxone®) for the Treatment of Opioid Use Disorder

TypeinterventionalSponsorRoyal Victoria Hospital, CanadaRan2022 to 2024Enrolled90ConditionsModerate to Severe Opioid Use DisorderArmsExtended Release Subcutaneous Buprenorphine, Immediate Release Sublingual Buprenorphine
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Marc GalanterDepartment of Psychiatry, School of Medicine, New York University, New York, New York.ORCID 0000-0002-1978-4453
John FeminoFemino Consultancy, Foster, Rhode Island.
Brooke HunterChestnut Health Systems, Normal, Illinois.
Mary HauserDominion Diagnostics, North Kingstown, Rhode Island.
21c Consultancy (United Kingdom) · GBChestnut Health Systems · USDominion Diagnostics (United States) · USNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesVariables contributing to the outcome of buprenorphine treatment for opiate use disorder have been studied, including patient characteristics and the treatment approach applied. It is also valuable to study the types of clinical facilities that can affect outcome.

methodsWe evaluated patients (N = 20 993) in 573 facilities where buprenorphine was prescribed. Urine drug test results were analyzed for those (N = 13 281) who had buprenorphine prescribed at least twice in the period January 2015 through June 2017. Facilities were divided into three categories: medication management (MM) only, limited psychosocial (LP) therapy, and recovery-oriented (with more extensive counseling and a 12-step orientation) (RO).

resultsUrine drug tests negative for other opioids at the time of the second buprenorphine prescription were 34% for MM, 56% for LP, and 62% for RO (P < .001). A comparison was made between the most recent and the established patients at the facilities. The decrement in urinalyses positive for other opioids in this latter comparison was 3% for MM, 7% for LP, and 23% for RO (P < .001). DISCUSSION AND

conclusionsIn a large sample of community settings, buprenorphine patients' urinalyses positive for opioids can vary considerably across treatment facilities, and more intensive recovery orientation may yield a better outcome in terms of secondary opioid use. SCIENTIFIC SIGNIFICANCE: The majority of buprenorphine patients are treated in community facilities. It is important that research be done by facility type in such settings in order to plan for optimal treatment. (© 2020 The Authors. The American Journal on Addictions published by Wiley Periodicals, Inc.;00:00-00).

Indexed as

BuprenorphineOpioid-Related DisordersAdultAnalgesics, OpioidDrug MonitoringFemaleHumansMaleMiddle AgedNarcotic AntagonistsOpiate Substitution TreatmentOutcome Assessment, Health CareSubstance Abuse DetectionUrinalysisAnalgesics, OpioidBuprenorphineNarcotic Antagonists

Identifiers

PMID32162434
PMCPMC7317980
OpenAlexW3011856614

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.