Evidence map›Paper›PMID 32162071›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2020

New minor groove covering DNA binding mode of dinuclear Pt(II) complexes with various pyridine-linked bridging ligands and dual anticancer-antiangiogenic activities.

Andjela A Franich, Marija D Živković, Tatjana Ilić-Tomić, Ivana S Đorđević, Jasmina Nikodinović-Runić, Aleksandar Pavić, Goran V Janjić, Snežana Rajković

Abstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Recent progress in the exploitation of anti-cancer small molecules targeting angiogenesis.Journal of enzyme inhibition and medicinal chemistry · 2025
    Review
  3. Characterization, modes of interactions with DNA/BSA biomolecules and anti-tumor activity of newly synthesized dinuclear platinum(II) complexes with pyridazine bridging ligand.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  4. Dinuclear platinum(II) complexes as the pattern for phosphate backbone binding: a new perspective for recognition of binding modes to DNA.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
  5. Article
  6. Review
  7. Monofunctional Platinum(II) Anticancer Agents.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  8. Benefits of Zebrafish Xenograft Models in Cancer Research.Frontiers in cell and developmental biology · 2021
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andjela A FranichFaculty of Science, Department of Chemistry, University of Kragujevac, R. Domanovića 12, 34000, Kragujevac, Serbia.
Marija D ŽivkovićFaculty of Medical Sciences, Department of Pharmacy, University of Kragujevac, Svetozara Markovića 69, 34000, Kragujevac, Serbia.
Tatjana Ilić-TomićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042, Belgrade 152, Serbia.
Ivana S ĐorđevićInstitute of Chemistry, Technology and Metallurgy, National Institute, University of Belgrade, Njegoševa 12, 11000, Belgrade, Serbia.
Jasmina Nikodinović-RunićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042, Belgrade 152, Serbia.
Aleksandar PavićInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042, Belgrade 152, Serbia. goran.janjic@ihtm.bg.ac.rs.
Goran V JanjićInstitute of Chemistry, Technology and Metallurgy, National Institute, University of Belgrade, Njegoševa 12, 11000, Belgrade, Serbia. goran.janjic@ihtm.bg.ac.rs.
Snežana RajkovićFaculty of Science, Department of Chemistry, University of Kragujevac, R. Domanovića 12, 34000, Kragujevac, Serbia. snezana@kg.ac.rs.
University of Belgrade · RSUniversity of Kragujevac · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New anticancer platinum(II) compounds simultaneously targeting tumor cells and tumor-derived neoangiogenesis, with new DNA interacting mode and large therapeutic window are appealing alternative to improve efficacy of clinical platinum chemotherapeutics. Herein, we describe three novel dinuclear [{Pt(en)Cl}

Indexed as

Angiogenesis InhibitorsAnimalsAntineoplastic AgentsBinding SitesCell Line, TumorCell ProliferationDNADose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansLigandsMolecular Docking SimulationMolecular StructureNeoplasms, ExperimentalNeovascularization, PathologicOrganoplatinum CompoundsAngiogenesis InhibitorsAntineoplastic Agentscalf thymus DNADNALigandsOrganoplatinum CompoundspyridinePyridinesDinuclear platinum(II) complexesDual anticancer and anti-angiogenic activityMinor groove covering

Identifiers

PMID32162071
OpenAlexW3012390987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.