ArticleJournal of neurology2020
Autonomic failure in Parkinson's disease is associated with striatal dopamine deficiencies.
Article in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Self-Reported Visual Complaints in People with Parkinson's Disease: A Systematic Review.Journal of Parkinson's disease · 2022Pooled it
- Patients with scans without evidence of dopaminergic deficit (SWEDD) do not have early Parkinson's disease: Analysis of the PPMI data.PloS one · 2021Trial
- Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging-Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Association of blood pressure variability with white matter hyperintensities and nigrostriatal dopaminergic deficits in drug-naïve Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Autonomic dysfunction in neurodegenerative disease.Nature reviews. Neuroscience · 2025Review
- Advances in autonomic dysfunction research in Parkinson's disease.Frontiers in aging neuroscience · 2025Review
- Gastric emptying time and its correlation with cardiac MIBG in body-first and brain-first subtype Parkinson's disease.Journal of neurology · 2024Article
- Clinical assessment and striatal dopaminergic activity in healthy controls and patients with Parkinson's disease: a Bayesian approach.Annals of nuclear medicine · 2024Article
- Impact of autonomic symptoms on the clinical course of Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Abnormal dopamine transporter imaging in pure autonomic failure: a potential biomarker of central nervous system involvement.European journal of neurology · 2024Article
- Baseline prevalence and longitudinal assessment of autonomic dysfunction in early Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- Epworth sleepiness scale is associated with increased striatal dopamine uptake in Parkinson's disease: a cross-sectional study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- In vivo cerebral metabolic and dopaminergic characteristics in multiple system atrophy with orthostatic hypotension.European journal of nuclear medicine and molecular imaging · 2024Article
- Radiomics for Parkinson's disease classification using advanced texture-based biomarkers.MethodsX · 2023Article
- Dopamine transporter binding in the brain is linked to irritable bowel syndrome in Parkinson's disease.Brain and behavior · 2023Article
- Dry eye in Parkinson's disease: a narrative review.Frontiers in neurology · 2023Review
- The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study.Frontiers in neurology · 2023Article
- Selected autonomic signs and symptoms as risk markers for phenoconversion and functional dependence in prodromal Parkinson's disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- Alpha-synucleinopathy reduces NMNAT3 protein levels and neurite formation that can be rescued by targeting the NAD+ pathway.Human molecular genetics · 2022Article
- Striatal dopamine transporter imaging in Parkinson's disease drug-naïve patients: focus on sexual dysfunction.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autonomic dysfunction is a common non-motor symptom in Parkinson's disease (PD). Dopamine and serotonin are known to play a role in autonomic regulation, and, therefore, PD-related degeneration of serotonergic and dopaminergic neurons in these regions may be associated with autonomic dysfunction. We sought to clarify the association between extrastriatal serotonergic and striatal dopaminergic degeneration and the severity of autonomic symptoms, including gastrointestinal, pupillomotor, thermoregulatory, cardiovascular, and urinary dysfunction. We performed hierarchical multiple regression analyses to determine the relationships between (extra)striatal serotonergic and dopaminergic degeneration and autonomic dysfunction in 310 patients with PD. We used [
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.