Evidence map›Paper›PMID 32162056›Full record

ArticleEuropean child & adolescent psychiatry2021

Predicting the risk of depression among adolescents in Nepal using a model developed in Brazil: the IDEA Project.

Rachel Brathwaite, Thiago Botter-Maio Rocha, Christian Kieling, Kamal Gautam, Suraj Koirala, Valeria Mondelli, Brandon Kohrt, Helen L Fisher

Abstract read
In one paragraph

Article in European child & adolescent psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rachel BrathwaiteSocial Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, London, SE5 8AF, UK.
Thiago Botter-Maio RochaDepartment of Psychiatry, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.
Christian KielingDepartment of Psychiatry, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.
Kamal GautamTranscultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, Nepal.
Suraj KoiralaTranscultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, Nepal.
Valeria MondelliDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Brandon Kohrt *Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, Nepal.
Helen L Fisher *Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, London, SE5 8AF, UK. helen.2.fisher@kcl.ac.uk.ORCID http://orcid.org/0000-0003-4174-2126

Funding

Strengthening Child Health Research Capacity in Resource Constrained Settings: Researcher Resilience Training (RRT)R25MH118935 · NIMH · WASHINGTON UNIVERSITY · PI SEAN JOE, Mary McKernan McKay · 2018 to 2026
$1.5M
PTSD And Other Health Consequences Of Exposure To TraumaF31MH075584 · NIMH · EMORY UNIVERSITY · PI KOHRT, BRANDON ALAN · 2005 to 2008
$90k
Academy of Medical Sciences (GB) GCRFNG\100281Medical Research Council MC_PC_MR/R019460/1MQ: Transforming Mental Health MQBF/1 IDEAMRF_ MRF-160-0005-ELP-MONDENIMH NIH HHS F31 MH075584NIMH NIH HHS R25 MH118935
6 · The paper itself

Abstract

The burden of adolescent depression is high in low- and middle-income countries (LMICs), yet research into prevention is lacking. Development and validation of models to predict individualized risk of depression among adolescents in LMICs is rare but crucial to ensure appropriate targeting of preventive interventions. We assessed the ability of a model developed in Brazil, a middle-income country, to predict depression in an existing culturally different adolescent cohort from Nepal, a low-income country with a large youth population with high rates of depression. Data were utilized from the longitudinal study of 258 former child soldiers matched with 258 war-affected civilian adolescents in Nepal. Prediction modelling techniques were employed to predict individualized risk of depression at age 18 or older in the Nepali cohort using a penalized logistic regression model. Following a priori exclusions for prior depression and age, 55 child soldiers and 71 war-affected civilians were included in the final analysis. The model was well calibrated, had good overall performance, and achieved good discrimination between depressed and non-depressed individuals with an area under the curve (AUC) of 0.73 (bootstrap-corrected 95% confidence interval 0.62-0.83). The Brazilian model comprising seven matching sociodemographic predictors, was able to stratify individualized risk of depression in a Nepali adolescent cohort. Further testing of the model's performance in larger socio-culturally diverse samples in other geographical regions should be attempted to test the model's wider generalizability.

Indexed as

AdolescentBrazilChildCohort StudiesDepressionFemaleHumansLongitudinal StudiesMaleNepalRisk FactorsAdolescenceExternal validationLMICMental healthPrediction modelRisk calculator

Identifiers

PMID32162056
PMCPMC7486232

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.