Evidence map›Paper›PMID 32161843›Full record

ArticleJBMR plus2020

Specific Commensal Bacterium Critically Regulates Gut Microbiota Osteoimmunomodulatory Actions During Normal Postpubertal Skeletal Growth and Maturation.

Jessica D Hathaway-Schrader, Nicole A Poulides, Matthew D Carson, Joy E Kirkpatrick, Amy J Warner, Brooks A Swanson, Eliza V Taylor, Michael E Chew, Sakamuri V Reddy, Bei Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Dysbiosis in the Gut-Liver Axis Is Associated With Low Bone Mass During Murine Cholestasis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. JBMR plus · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Commensal gut bacterium critically regulates alveolar bone homeostasis.Laboratory investigation; a journal of technical methods and pathology · 2022
    Article
  14. Article
  15. Review
  16. Frontiers in immunology · 2022
    Article
  17. Antimicrobial-induced oral dysbiosis exacerbates naturally occurring alveolar bone loss.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  18. Article
  19. Article
  20. Gut-Bone Axis: A Non-Negligible Contributor to Periodontitis.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jessica D Hathaway-SchraderDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Nicole A PoulidesDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Matthew D CarsonDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Joy E KirkpatrickDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Amy J WarnerDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Brooks A SwansonDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Eliza V TaylorDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Michael E ChewDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Sakamuri V ReddyDepartment of Pediatrics-Division of Endocrinology College of Medicine, Medical University of South Carolina Charleston SC USA.
Bei LiuDepartment of Microbiology and Immunology College of Medicine, Medical University of South Carolina Charleston SC USA.
Caroline WestwaterDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.
Chad M NovinceDepartment of Oral Health Sciences College of Dental Medicine, Medical University of South Carolina Charleston SC USA.ORCID https://orcid.org/0000-0002-0318-7494
Medical University of South Carolina · US

Funding

The role of SMAD1 and SATB2 in colon patterningP20GM130457 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI STEPHEN A DUNCAN · 2020 to 2026
$18.7M
T-COHR: Training in Craniofacial and Oral Health ResearchT32DE017551 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YAO, HAI · 2006 to 2025
$10.3M
Impact of the Microbiome on Osteoimmunology and Skeletal DevelopmentK08DE025337 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI NOVINCE, CHAD MICHAEL · 2016 to 2020
$679k
Validation and Development of KDM4B Inhibitors to Target Peridontal DiseaseF30DE027290 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI GERASCO, JOY ELIZABETH · 2017 to 2020
$193k
NIDCR NIH HHS F30 DE027290NIDCR NIH HHS K08 DE025337NIDCR NIH HHS L40 DE025410NIDCR NIH HHS T32 DE017551NIGMS NIH HHS P20 GM130457
6 · The paper itself

Abstract

The commensal gut microbiota critically regulates immunomodulatory processes that influence normal skeletal growth and maturation. However, the influence of specific microbes on commensal gut microbiota osteoimmunoregulatory actions is unknown. We have shown previously that the commensal gut microbiota enhances T

Indexed as

BONE MODELING/REMODELINGGUT MICROBIOTAOSTEOCLASTSOSTEOIMMUNOLOGY

Identifiers

PMID32161843
PMCPMC7059828
OpenAlexW2999000800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.