Evidence map›Paper›PMID 32161765›Full record

ArticleFrontiers in veterinary science2020

Activities of Endochin-Like Quinolones Against

Naja Eberhard, Vreni Balmer, Joachim Müller, Norbert Müller, Rolf Winter, Soviti Pou, Aaron Nilsen, Mike Riscoe, Samuel Francisco, Alexandre Leitao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Synthesis of Deuterated Endochin-Like Quinolones.Journal of labelled compounds & radiopharmaceuticals · 2024
    Article
  6. Review
  7. Article
  8. Structure-activity relationships ofExpert opinion on drug discovery · 2022
    Article
  9. Dual inhibition of theFrontiers in veterinary science · 2022
    Article
  10. Article
  11. Article
  12. Pathogens (Basel, Switzerland) · 2020
    Article
  13. Expert opinion on therapeutic targets
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Naja EberhardVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Vreni BalmerVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Joachim MüllerVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Norbert MüllerVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Rolf WinterVA Portland Health Care System Research and Development Service, Portland, OR, United States.
Soviti PouVA Portland Health Care System Research and Development Service, Portland, OR, United States.
Aaron NilsenVA Portland Health Care System Research and Development Service, Portland, OR, United States.
Mike RiscoeVA Portland Health Care System Research and Development Service, Portland, OR, United States.
Samuel FranciscoFaculdade de Medicina Veterinária, CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Universidade de Lisboa, Lisbon, Portugal.
Alexandre LeitaoFaculdade de Medicina Veterinária, CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Universidade de Lisboa, Lisbon, Portugal.
J Stone DoggettVA Portland Health Care System Research and Development Service, Portland, OR, United States.
Andrew HemphillVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
University of Bern · CHVA Portland Health Care System · USUniversity of Lisbon · PT

Funding

Optimizing ELQs for Treatment and Prevention of MalariaR01AI100569 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Michael Kevin RISCOE · 2014 to 2026
$8.0M
Novel Therapeutic Strategies for ELQ-422, a preclinical Toxoplasmosis Drug CandidateI01BX004522 · VA · PORTLAND VA MEDICAL CENTER · PI Joseph Stone Doggett · 2019 to 2026
–
BLRD VA I01 BX004522BLRD VA IK2 BX002440NIAID NIH HHS R01 AI100569
6 · The paper itself

Abstract

Endochin-like quinolones (ELQs) potently inhibit the proliferation of

Indexed as

Besnoitia besnoitielectron microscopyendochin-like quinolonesmitochondrial inhibitionSAR

Identifiers

PMID32161765
PMCPMC7054222
OpenAlexW3006790062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.