Evidence map›Paper›PMID 32161756›Full record

ReviewFrontiers in cell and developmental biology2020

Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium.

Kai Sen Tan, Rachel Liyu Lim, Jing Liu, Hsiao Hui Ong, Vivian Jiayi Tan, Hui Fang Lim, Kian Fan Chung, Ian M Adcock, Vincent T Chow, De Yun Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Mucins and Respiratory Virus Infection.Annual review of virology · 2026
    Review
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Targeting respiratory virus-induced reactive oxygen species in airways diseases.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Mitogen-activated protein kinase-guided drug discovery for post-viral and related types of lung disease.European respiratory review : an official journal of the European Respiratory Society · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Kai Sen TanDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Rachel Liyu LimInfectious Disease Research and Training Office, National Centre for Infectious Diseases, Singapore, Singapore.
Jing LiuDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Hsiao Hui OngDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Vivian Jiayi TanDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Hui Fang LimDivision of Respiratory and Critical Care Medicine, National University Hospital, Singapore, Singapore.
Kian Fan ChungAirway Disease, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.
Ian M AdcockAirway Disease, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.
Vincent T ChowDepartment of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
De Yun WangDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
National University of Singapore · SGImperial College London · GBNational Centre for Infectious Diseases · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory virus infection is one of the major sources of exacerbation of chronic airway inflammatory diseases. These exacerbations are associated with high morbidity and even mortality worldwide. The current understanding on viral-induced exacerbations is that viral infection increases airway inflammation which aggravates disease symptoms. Recent advances in

Indexed as

acute exacerbationchronic airway inflammatory diseasesepitheliumrespiratory virusupper airway

Identifiers

PMID32161756
PMCPMC7052386
OpenAlexW3007905887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.