Evidence map›Paper›PMID 32161746›Full record

ReviewFrontiers in chemistry2020

Biochemical Characterization of Oyster and Clam Galectins: Selective Recognition of Carbohydrate Ligands on Host Hemocytes and

Gerardo R Vasta, Chiguang Feng, Satoshi Tasumi, Kelsey Abernathy, Mario A Bianchet, Iain B H Wilson, Katharina Paschinger, Lai-Xi Wang, Muddasar Iqbal, Anita Ghosh and 4 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. A brief history of galectin evolution.Frontiers in immunology · 2023
    Article
  4. Bivalve Haemocyte Subpopulations: A Review.Frontiers in immunology · 2022
    Review
  5. Article
  6. A qPCR-Based Survey ofPathogens (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Gerardo R VastaDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Marine and Environmental Technology, Baltimore, MD, United States.
Chiguang FengDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Marine and Environmental Technology, Baltimore, MD, United States.
Satoshi TasumiDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Marine and Environmental Technology, Baltimore, MD, United States.
Kelsey AbernathyDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Marine and Environmental Technology, Baltimore, MD, United States.
Mario A BianchetDepartments of Neurology, and Biophysics and Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Iain B H WilsonDepartment für Chemie, Universität für Bodenkultur, Vienna, Austria.
Katharina PaschingerDepartment für Chemie, Universität für Bodenkultur, Vienna, Austria.
Lai-Xi WangDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD, United States.
Muddasar IqbalDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Marine and Environmental Technology, Baltimore, MD, United States.
Anita GhoshDepartments of Neurology, and Biophysics and Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Mohammed N AminDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD, United States.
Brina SmithDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Marine and Environmental Technology, Baltimore, MD, United States.
Sean BrownDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Marine and Environmental Technology, Baltimore, MD, United States.
Aren VistaDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Marine and Environmental Technology, Baltimore, MD, United States.
University of Maryland, Baltimore · USUniversity of Maryland, College Park · USCoppin State University · USJohns Hopkins Medicine · USJohns Hopkins University · US

Funding

Covergent Chemoenzymatic Synthesis of Glycopeptides and GlycoproteinsR01GM080374 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI WANG, LAI-XI · 2007 to 2021
$3.9M
Austrian Science Fund FWF P 21946NIGMS NIH HHS R01 GM080374
6 · The paper itself

Abstract

Both vertebrates and invertebrates display active innate immune mechanisms for defense against microbial infection, including diversified repertoires of soluble and cell-associated lectins that can effect recognition and binding to potential pathogens, and trigger downstream effector pathways that clear them from the host internal milieu. Galectins are widely distributed and highly conserved lectins that have key regulatory effects on both innate and adaptive immune responses. In addition, galectins can bind to exogenous ("non-self") carbohydrates on the surface of bacteria, enveloped viruses, parasites, and fungi, and function as recognition receptors and effector factors in innate immunity. Like most invertebrates, eastern oysters (

Indexed as

biochemical characterizationbivalve hemocytecarbohydrate recognitiongalectinperkinsus parasites

Identifiers

PMID32161746
PMCPMC7053492
OpenAlexW3006995867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.