Evidence map›Paper›PMID 32161681›Full record

ArticleThe South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa2020

Psycho-demographic and clinical predictors of medication adherence in patients with bipolar I disorder in a university hospital in Egypt.

Tarek A Okasha, Doaa N Radwan, Hussien Elkholy, Heba M F M Hendawy, Eman M M E Shourab, Ramy R A Teama, Ahmed S Abdelgawad

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Article in The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tarek A OkashaDepartment of Neurology and Psychiatry - Institute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-4819-1497
Doaa N RadwanDepartment of Neurology and Psychiatry - Institute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-0490-9401
Hussien ElkholyDepartment of Neurology and Psychiatry - Institute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID https://orcid.org/0000-0003-2132-6336
Heba M F M HendawyDepartment of Neurology and Psychiatry - Institute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-8505-9727
Eman M M E ShourabDepartment of Neurology and Psychiatry - Institute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID https://orcid.org/0000-0003-4845-7686
Ramy R A TeamaDepartment of Neurology and Psychiatry - Institute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID https://orcid.org/0000-0001-5492-0441
Ahmed S AbdelgawadMinistry of Health and Population, Cairo, Egypt.ORCID https://orcid.org/0000-0002-7928-4768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor adherence to treatment is one of the main challenges to symptom control and preventing recurrence in bipolar disorder (BD). Numerous studies have established an association between patients' poor adherence and an increased risk of recurrence, relapse of the symptoms and admission to hospital.

aimTo study the socio-demographic and clinical factors associated with medication nonadherence in patients with BD who were admitted to the hospital.

settingThe study was conducted at the Institute of Psychiatry, Ain Shams University.

methodsA 1-year longitudinal prospective study of 110 patients, aged 18-60 years, with BD-I. Young Mania Rating Scale, Clinical Global Impression, Global Assessment of Functioning, Sheehan Disability Scale and Insight and Treatment Attitude Questionnaire were applied before and 6 months after discharge. Adherence was measured using the Morisky 8-Item Medication Adherence Scale. Sociodemographic data and level of functioning were studied in relation to adherence.

resultsHigher adherence was noticed in female, married and older patients and those with a higher level of education. However, low adherence was more common in male, non-married and less educated patients. Follow-up after 6 months revealed that the high adherence group scored the lowest in terms of disability. Meanwhile, the low adherence group scored the highest scores in disability.

conclusionSeveral socio-demographic and clinical variables were found to be associated with a low adherence rate to the prescribed medication in patients with BD-I. Age and impaired insight were found to be significant predictive factors for non-adherence.

Indexed as

adherencebipolar disorderillnessinsightmedicationseverity

Identifiers

PMID32161681
PMCPMC7059429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.