Evidence map›Paper›PMID 32161616›Full record

ArticleFrontiers in genetics2020

HIF-1 Has a Central Role in

Laura Romanelli-Credrez, Maria Doitsidou, Mark J Alkema, Gustavo Salinas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Laura Romanelli-CredrezLaboratorio de Biología de Gusanos. Unidad Mixta, Departamento de Biociencias, Facultad de Química, Universidad de la República-Institut Pasteur de Montevideo, Montevideo, Uruguay.
Maria DoitsidouCentre for Discovery Brain Sciences (CDBS), University of Edinburgh, Edinburgh, United Kingdom.
Mark J AlkemaNeurobiology Department, University of Massachusetts Medical School, Worcester, MA, United States.
Gustavo SalinasLaboratorio de Biología de Gusanos. Unidad Mixta, Departamento de Biociencias, Facultad de Química, Universidad de la República-Institut Pasteur de Montevideo, Montevideo, Uruguay.
Institut Pasteur de Montevideo · UYUniversity of Edinburgh · GBUniversity of Massachusetts Chan Medical School · US

Funding

The gut brain axis: microbial impact on neural functionR01NS107475 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ALKEMA, MARK · 2018 to 2022
$1.8M
The impact of stress neurohormones on health and agingR01GM140480 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ALKEMA, MARK · 2021 to 2024
$1.5M
NIGMS NIH HHS R01 GM140480NINDS NIH HHS R01 NS107475
6 · The paper itself

Abstract

Selenium is a trace element for most organisms; its deficiency and excess are detrimental. Selenium beneficial effects are mainly due to the role of the 21

Indexed as

Caenorhabditis elegansCYSL-1EGL-9HIF-1seleniteseleniumstresssulfide

Identifiers

PMID32161616
PMCPMC7052493
OpenAlexW3007667066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.