Evidence map›Paper›PMID 32161464›Full record

ArticleTherapeutics and clinical risk management2020

Metastatic Hepatic Epithelioid Hemangioendothelioma Treated with Olaratumab: A Falling Star Rising?

Anastasios Kyriazoglou, Konstantinos Koutsoukos, Flora Zagouri, Michalis Liontos, Efthimios Dimitriadis, Dina Tiniakos, Meletios Athanasios Dimopoulos

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutics and clinical risk management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Anastasios KyriazoglouDepartment of Clinical Therapeutics, General Hospital Alexandra, Athens, Greece.
Konstantinos KoutsoukosDepartment of Clinical Therapeutics, General Hospital Alexandra, Athens, Greece.
Flora ZagouriDepartment of Clinical Therapeutics, General Hospital Alexandra, Athens, Greece.
Michalis LiontosDepartment of Clinical Therapeutics, General Hospital Alexandra, Athens, Greece.ORCID 0000-0001-7192-4575
Efthimios DimitriadisDepartment of Genetics, Agios Savvas Hospital, Athens, Greece.
Dina TiniakosDepartment of Pathology Aretaion Hospital, National & Kapodistrian University of Athens, Athens, Greece.
Meletios Athanasios DimopoulosDepartment of Clinical Therapeutics, General Hospital Alexandra, Athens, Greece.
Alexandra Hospital · GRNational and Kapodistrian University of Athens · GRSt Savas Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelioid hemangioendothelioma (EHE) is a rare vascular malignant tumor with indolent course. Liver transplantation for local disease is the treatment of choice. In the metastatic setting there is no consensus regarding the appropriate systemic treatment. We present two cases of metastatic hepatic epithelioid hemangioendothelioma (hEHE) treated with the combination of Doxorubicin and Olaratumab. Both patients showed Stable Disease (SD) as a response, after the completion of six cycles of this combination therapy.

Indexed as

1st line treatmentmetastatic hepatic epithelioid hemangioendotheliomaOlaratumab and Doxorubicin

Identifiers

PMID32161464
PMCPMC7051805
OpenAlexW3006938590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.