Evidence map›Paper›PMID 32161456›Full record

ArticleInternational journal of nanomedicine2020

A Radio-Nano-Platform for T1/T2 Dual-Mode PET-MR Imaging.

Yaser Hadi Gholami, Hushan Yuan, Moses Q Wilks, Richard Maschmeyer, Marc D Normandin, Lee Josephson, Georges El Fakhri, Zdenka Kuncic

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Radiolabeled AgScientific reports · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. MnCOTheranostics · 2022
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yaser Hadi GholamiFaculty of Science, School of Physics, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-7161-9367
Hushan YuanGordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Moses Q WilksGordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Richard MaschmeyerFaculty of Science, School of Physics, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-3805-5440
Marc D NormandinGordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1645-523X
Lee JosephsonGordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-7230-7015
Georges El FakhriGordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Zdenka KuncicFaculty of Science, School of Physics, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0001-6765-3215
Harvard University · USThe University of Sydney · AU

Funding

Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Kira Grogg · 2017 to 2026
$14.8M
NIBIB NIH HHS P41 EB022544
6 · The paper itself

Abstract

purposeThis study aimed to develop a chelate-free radiolabeled nanoparticle platform for simultaneous positron emission tomography (PET) and magnetic resonance (MR) imaging that provides contrast-enhanced diagnostic imaging and significant image quality gain by integrating the high spatial resolution of MR with the high sensitivity of PET.

methodsA commercially available super-paramagnetic iron oxide nanoparticle (SPION) (Feraheme

resultsHigh RCY (92%) and RCP (98%) of the [

conclusionOur results demonstrate FH is a highly suitable SPION-based platform for chelate-free labeling of PET tracers for hybrid PET-MR. The high RCY and RCP confirmed the robustness of the chelate-free HIR technique. An overall image quality gain was achieved compared to PET- or MR-alone imaging with a relatively low dosage of [

Indexed as

Chromatography, GelChromatography, Thin LayerContrast MediaFerrosoferric OxideHumansMagnetic Resonance ImagingMagnetite NanoparticlesPhantoms, ImagingPositron-Emission TomographyRadioisotopesRadiopharmaceuticalsSignal-To-Noise RatioZirconiumContrast MediaFerrosoferric OxideMagnetite NanoparticlesRadioisotopesRadiopharmaceuticalsZirconiumZirconium-89HIRMRImultimodal imagingPETradiolabelingSPIONs

Identifiers

PMID32161456
PMCPMC7049573
OpenAlexW3008008497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.