Evidence map›Paper›PMID 32161257›Full record

ArticleNature communications2020

UBB pseudogene 4 encodes functional ubiquitin variants.

Marie-Line Dubois, Anna Meller, Sondos Samandi, Mylène Brunelle, Julie Frion, Marie A Brunet, Amanda Toupin, Maxime C Beaudoin, Jean-François Jacques, Dominique Lévesque and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Eukaryotic Microproteins.Annual review of biochemistry · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Almost 50 Years of Monomeric Extracellular Ubiquitin (eUb).Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  17. Article
  18. Article
  19. Deubiquitylating Enzymes in Cancer and Immunity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Marie-Line DuboisDepartment of Immunology and Cell Biology, Sherbrooke, QC, Canada.
Anna MellerDepartment of Immunology and Cell Biology, Sherbrooke, QC, Canada.
Sondos SamandiDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada.
Mylène BrunelleDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada.
Julie FrionDepartment of Immunology and Cell Biology, Sherbrooke, QC, Canada.
Marie A BrunetDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada.
Amanda ToupinDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada.
Maxime C BeaudoinDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada.
Jean-François JacquesDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada.ORCID http://orcid.org/0000-0002-0465-0313
Dominique LévesqueDepartment of Immunology and Cell Biology, Sherbrooke, QC, Canada.
Michelle S ScottDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada.
Pierre LavigneDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada.
Xavier RoucouDepartment of Biochemistry and Functional Genomics, Sherbrooke, QC, Canada. xavier.roucou@usherbrooke.ca.ORCID http://orcid.org/0000-0001-9370-5584
François-Michel BoisvertDepartment of Immunology and Cell Biology, Sherbrooke, QC, Canada. fm.boisvert@usherbrooke.ca.ORCID http://orcid.org/0000-0001-8882-8619
Q & T Research · CAUniversité de Sherbrooke · CA

Funding

CIHR 398925
6 · The paper itself

Abstract

Pseudogenes are mutated copies of protein-coding genes that cannot be translated into proteins, but a small subset of pseudogenes has been detected at the protein level. Although ubiquitin pseudogenes represent one of the most abundant pseudogene families in many organisms, little is known about their expression and signaling potential. By re-analyzing public RNA-sequencing and proteomics datasets, we here provide evidence for the expression of several ubiquitin pseudogenes including UBB pseudogene 4 (UBBP4), which encodes Ub

Indexed as

Cell DivisionCell NucleusCloning, MolecularCRISPR-Cas SystemsDatasets as TopicGene Knockout TechniquesHEK293 CellsHeLa CellsHumansLamin Type AProteomicsPseudogenesRNA-SeqUbiquitinUbiquitinationLamin Type ALMNA protein, humanUbiquitin

Identifiers

PMID32161257
PMCPMC7066184
OpenAlexW3012531077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.