ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2021
Comparison of the Diagnostic Value of Mono-exponential, Bi-exponential, and Stretched Exponential Signal Models in Diffusion-weighted MR Imaging for Differentiating Benign and Malignant Hepatic Lesions.
Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Objective value of the apparent diffusion coefficient (ADC) map from ultrahigh b-value diffusion-weighted imaging (DWI) in 3T MRI as a non-invasive predictor for Gleason score in prostate cancer.Quantitative imaging in medicine and surgery · 2026Article
- Application of Intravoxel Incoherent Motion in the Prediction of Intra-Tumoral Tertiary Lymphoid Structures in Hepatocellular Carcinoma.Journal of hepatocellular carcinoma · 2025Article
- The Value of CT Perfusion Parameters and Apparent Diffusion Coefficient Value of Magnetic Resonance Diffusion Weighted Imaging in Diagnosis of Hepatocellular Carcinoma.Computational and mathematical methods in medicine · 2022Article
- The Role of Non-Gaussian Models of Diffusion Weighted MRI in Hepatocellular Carcinoma: A Systematic Review.Journal of clinical medicine · 2021Review
- Quantitative magnetic resonance imaging for focal liver lesions: bridging the gap between research and clinical practice.The British journal of radiology · 2021Review
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Abstract
purposeTo compare the diagnostic value of mono-exponential, bi-exponential, and stretched exponential diffusion-weighted imaging (DWI) for differentiating benign and malignant hepatic lesions.
methodsThis prospective study was approved by our Institutional Review Board and the patients provided written informed consent. Magnetic resonance imaging was acquired for 56 patients with suspected liver disease. This identified 90 focal liver lesions with a maximum diameter >10 mm, of which 47 were benign and 43 were malignant. Using home-built software, two radiologists measured the DWI parameters of hepatic lesions for three models: the apparent diffusion coefficient (ADC) from a mono-exponential model; the true diffusion coefficient (D), pseudo-diffusion coefficient (D
resultsADC, D, D
conclusionDDC values obtained from the stretched exponential model could be also used as a quantitative imaging biomarker for differentiating benign and malignant hepatic lesions, however, the diagnostic performance was comparable with ADC values.
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