Evidence map›Paper›PMID 32161145›Full record

ArticlemSphere2020

ZupT Facilitates Clostridioides difficile Resistance to Host-Mediated Nutritional Immunity.

Joseph P Zackular, Reece J Knippel, Christopher A Lopez, William N Beavers, C Noel Maxwell, Walter J Chazin, Eric P Skaar

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Unravelling three-way interactions betweenJournal of medical microbiology · 2025
    Review
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  4. Article
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  7. Article
  8. Article
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  10. TheMicrobiology spectrum · 2023
    Article
  11. Article
  12. Microbiology (Reading, England) · 2023
    Review
  13. Review
  14. Review
  15. Capturing the environment of the Clostridioides difficile infection cycle.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Microbial genomics · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Joseph P Zackular *Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3228-3055
Reece J Knippel *Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-3129-5468
Christopher A LopezDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
William N BeaversDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
C Noel MaxwellDepartment of Biochemistry, Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, USA.
Walter J ChazinDepartment of Biochemistry, Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, USA.
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA eric.skaar@vumc.org.
Vanderbilt University Medical Center · USVanderbilt University · USChildren's Hospital of Philadelphia · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Host-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2M
Chemistry-Biology Interface Training GrantT32GM065086 · NIGMS · VANDERBILT UNIVERSITY · PI BACHMANN, BRIAN O, SULIKOWSKI, GARY ALLEN · 2002 to 2022
$7.0M
MOLECULAR PARASITOLOGY TRAINING PROGRAMT32AI007281 · NIAID · MEHARRY MEDICAL COLLEGE · PI NDE, PIUS N · 1985 to 2025
$3.2M
The Impact of Vancomycin-Resistant Entercoccus on Clostridium difficile InfectionK22AI137220 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI ZACKULAR, JOSEPH PAUL · 2019 to 2020
$270k
The impact of dietary metals on the gut microbiome and Clostridium difficile infectionF32AI120553 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZACKULAR, JOSEPH PAUL · 2015 to 2017
$109k
NIAID NIH HHS F32 AI120553NIAID NIH HHS K22 AI137220NIAID NIH HHS R01 AI101171NIAID NIH HHS T32 AI007281NIDDK NIH HHS P30 DK058404NIGMS NIH HHS T32 GM065086
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBacterial ProteinsCarrier ProteinsClostridioides difficileClostridium InfectionsDisease Models, AnimalHost-Pathogen InteractionsHumansImmunity, InnateLeukocyte L1 Antigen ComplexMembrane Transport ProteinsMiceNutrientsZincBacterial ProteinsCarrier ProteinsLeukocyte L1 Antigen ComplexMembrane Transport ProteinsNutrientsZinczinc-binding proteinClostridium difficilehost-pathogen interactionsinfectious diseasenutrient transport

Identifiers

PMID32161145
PMCPMC7067591
OpenAlexW3011861303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.