Evidence map›Paper›PMID 32161066›Full record

ArticleBMJ open respiratory research2020

Novel measure of lung function for assessing disease activity in asthma.

Nicholas M J Smith, John Couper, Christopher J Fullerton, Graham Richmond, Nick P Talbot, Gus Hancock, Ian Pavord, Grant A D Ritchie, Peter A Robbins, Nayia Petousi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nicholas M J SmithDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, UK.ORCID 0000-0003-3206-9793
John CouperDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, UK.
Christopher J FullertonDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0003-1306-2481
Graham RichmondDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, UK.ORCID 0000-0003-2999-5067
Nick P TalbotDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0002-9186-8950
Gus HancockDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, UK.ORCID 0000-0003-1166-4104
Ian PavordOxford NIHR Respiratory Biomedical Research Centre, University of Oxford, Oxford, UK.
Grant A D RitchieDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, UK.ORCID 0000-0003-1663-7770
Peter A RobbinsDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0002-4975-0609
Nayia PetousiDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK nayia.petousi@dpag.ox.ac.uk.ORCID 0000-0002-5524-020X
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn asthma, lung function measures are often discordant with clinical features such as disease activity or control.

methodsWe investigated a novel technique that provides a measure (σCL) of unevenness (inhomogeneity) in lung inflation/deflation. In particular, we compared σCL with FEV

resultsσCL correlated modestly with FEV DISCUSSION: We conclude that σCL shows promise as an objective measure of disease activity in asthma.

Indexed as

Forced Expiratory VolumePulmonary Gas ExchangeSeverity of Illness IndexAdultAgedAlbuterolAsthmaBronchodilator AgentsCase-Control StudiesFemaleHumansLungMaleMiddle AgedSpirometryAlbuterolBronchodilator Agentsasthma

Identifiers

PMID32161066
PMCPMC7066624
OpenAlexW3010930616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.