Evidence map›Paper›PMID 32161063›Full record

ReviewDevelopment (Cambridge, England)2020

Skeletal stem cells: insights into maintaining and regenerating the skeleton.

Maxwell A Serowoky, Claire E Arata, J Gage Crump, Francesca V Mariani

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Stage-resolved geography of mouse skeletal stem cells.Journal of bone and mineral metabolism · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Challenges of engineering a functional growth plateFrontiers in bioengineering and biotechnology · 2025
    Review
  9. [Role of R-spondin 2 on osteogenic differentiation of bone marrow mesenchymal stem cells and bone metabolism in ovariectomized mice].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
    Article
  10. MSX1Stem cell reports · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Sfrp4 is required to maintain Ctsk-lineage periosteal stem cell niche function.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maxwell A SerowokyDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Claire E ArataDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
J Gage CrumpDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA gcrump@usc.edu fmariani@usc.edu.ORCID 0000-0002-3209-0026
Francesca V MarianiDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA gcrump@usc.edu fmariani@usc.edu.ORCID 0000-0003-1619-8763

Funding

Progenitor Regulation in Craniofacial Development and RegenerationR35DE027550 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D · 2017 to 2024
$8.0M
Training in Developmental Biology, Stem Cells and RegenerationT32HD060549 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Gage D Crump · 2011 to 2026
$2.5M
Genetic regulation of the cartilage callus during large-scale bone repairR01AR069700 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MARIANI, FRANCESCA V · 2016 to 2021
$2.4M
Role of Ossifying Chondrocytes in Regeneration of the Adult Jaw SkeletonR21DE023899 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D · 2014 to 2015
$453k
Development of a Mammalian Model for Rib RepairR21AR064462 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MARIANI, FRANCESCA V · 2013 to 2014
$384k
NIAMS NIH HHS R01 AR069700NIAMS NIH HHS R21 AR064462NICHD NIH HHS T32 HD060549NIDCR NIH HHS R21 DE023899NIDCR NIH HHS R35 DE027550
6 · The paper itself

Abstract

Skeletal stem cells (SSCs) generate the progenitors needed for growth, maintenance and repair of the skeleton. Historically, SSCs have been defined as bone marrow-derived cells with inconsistent characteristics. However, recent

Indexed as

AnimalsBone DevelopmentBone Marrow CellsBone RegenerationChondrocytesGrowth PlateHumansMiceOsteoblastsOsteogenesisPeriosteumStem CellsZebrafishBone marrowGrowth platePeriosteumSkeletal repairSkeletonStem cells

Identifiers

PMID32161063
PMCPMC7075071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.