ArticleJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2020
Potential Impact of Cessation Interventions at the Point of Lung Cancer Screening on Lung Cancer and Overall Mortality in the United States.
Article in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Effectiveness and implementation challenges of mobile low-dose computed tomography units for early lung cancer detection: a systematic review.Frontiers in public health · 2026Pooled it
- Trial
- Effect of a Personalized Tobacco Treatment Intervention on Smoking Abstinence in Individuals Eligible for Lung Cancer Screening.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2024Trial
- A Randomized Trial of Telephone-Based Smoking Cessation Treatment in the Lung Cancer Screening Setting.Journal of the National Cancer Institute · 2022Trial
- Cost-Effectiveness of a Telephone-Based Smoking Cessation Randomized Trial in the Lung Cancer Screening Setting.JNCI cancer spectrum · 2022Trial
- Cost-Effectiveness of Smoking Cessation Interventions Integrated Into Lung Cancer Screening.JAMA network open · 2026Article
- Interventions for smoking cessation in people undergoing lung cancer screening.The Cochrane database of systematic reviews · 2026Article
- Markov-model cost-effectiveness evaluation of a cessation programme when tobacco policies are comprehensive.BMJ open · 2026Article
- National Screening, National Responsibility: Turning Promise Into Progress for Lung Cancer Care.The Medical journal of Australia · 2026Article
- Missed opportunities for tobacco dependence treatment among U.S. veterans referred for lung Cancer screening: An observational cohort study.Preventive medicine reports · 2025Article
- Structured narrative review on lung cancer screening: current evidence, clinical practice implications and implementation insights from a multidisciplinary task force and patient representatives.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Regional trends and disparities of lung cancer mortality in the United States, 1999-2022: a retrospective cohort study.Respiratory research · 2025Article
- Updates in Lung Cancer Screening: A Decade of Evidence.Seminars in respiratory and critical care medicine · 2025Review
- Natural history models for lung Cancer: A scoping review.Lung cancer (Amsterdam, Netherlands) · 2025Article
- "Because That is the Right Thing to do": A Focus Group Study of Australian Expert Perspectives on Offering Smoking Cessation Support in Lung Cancer Screening.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Self-blaming as a barrier to lung cancer screening and smoking cessation programs in Italy. A qualitative study.PloS one · 2025Article
- Beyond lung cancer screening, an opportunity for early detection of chronic obstructive pulmonary disease and cardiovascular diseases.JNCI cancer spectrum · 2024Article
- Uptake and 4-week quit rates from an opt-out co-located smoking cessation service delivered alongside community-based low-dose computed tomography screening within the Yorkshire Lung Screening Trial.The European respiratory journal · 2024Article
- Article
- Contribution of smoking, disease history, and survival to lung cancer disparities in Black individuals.Journal of the National Cancer Institute. Monographs · 2023Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
introductionAnnual lung cancer screening with low-dose computed tomography is recommended for adults aged 55 to 80 years with a greater than or equal to 30 pack-year smoking history who currently smoke or quit within the past 15 years. The 50% who are current smokers should be offered cessation interventions, but information about the impact of adding cessation to screening is limited.
methodsWe used an established lung cancer simulation model to compare the effects on mortality of a hypothetical one-time cessation intervention and annual screening versus annual screening only among screen-eligible individuals born in 1950 or 1960. Model inputs were derived from national data and included smoking history, probability of quitting with and without intervention, lung cancer risk and treatment effectiveness, and competing tobacco-related mortality. We tested the sensitivity of results under different assumptions about screening use and cessation efficacy.
resultsSmoking cessation reduces lung cancer mortality and delays overall deaths versus screening only across all assumptions. For example, if screening was used by 30% of screen-eligible individuals born in 1950, adding an intervention with a 10% quit probability reduces lung cancer deaths by 14% and increases life years gained by 81% compared with screening alone. The magnitude of cessation benefits varied under screening uptake rates, cessation effectiveness, and birth cohort.
conclusionsSmoking cessation interventions have the potential to greatly enhance the impact of lung cancer screening programs. Evaluation of specific interventions, including costs and feasibility of implementation and dissemination, is needed to determine the best possible strategies and realize the full promise of lung cancer screening.
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