Evidence map›Paper›PMID 32160927›Full record

ArticleInfectious diseases of poverty2020

Factors associated with cutaneous ulcers among children in two yaws-endemic districts in Ghana.

Rafiq Nii Attoh Okine, Bismark Sarfo, Richard M Adanu, Cynthia Kwakye-Maclean, Francis Adjei Osei

Open access · goldAbstract read
In one paragraph

Article in Infectious diseases of poverty, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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  11. Gold Panning-Related Chronic Cutaneous Ulcers in Guinea, West Africa.The American journal of tropical medicine and hygiene · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rafiq Nii Attoh OkineWorld Health Organization (WHO), Country Office for Ghana, Accra, Ghana.
Bismark SarfoDepartment of Epidemiology and Disease Control, School of Public Health, College of Health, Sciences, University of Ghana, Accra, Ghana.
Richard M AdanuDepartment of Epidemiology and Disease Control, School of Public Health, College of Health, Sciences, University of Ghana, Accra, Ghana.
Cynthia Kwakye-MacleanNational Program Office, National Yaws Eradication Program (NYEP), Accra, Ghana.
Francis Adjei OseiPublic Health Unit, Komfo-Anokye Teaching Hospital, Kumasi, Ghana. francisph1@hotmail.com.ORCID http://orcid.org/0000-0003-1094-813X
University of Ghana · GHGhana Health Service · GHKomfo Anokye Teaching Hospital · GH

Funding

World Health Organization 001World Health Organization WHO/TDR Implementation Science Fellowship Program
6 · The paper itself

Abstract

backgroundYaws is a chronic relapsing disease caused by Treponema pallidum subspecies pertunue, which can result in severe disability and deformities. Children below the age of 15 years in resource-poor communities are the most affected. Several non-specific factors facilitate the continuous transmission and resurgence of the disease. Endemic communities in rural Ghana continue to report cases despite the roll out of several intervention strategies in the past years. The objective of this study was to determine the factors associated with cutaneous ulcers among children in two yaws-endemic districts in Ghana.

methodsA community-based unmatched 1:2 case-control study was conducted among children between 1 and 15 years. Data on socio-demographic, environmental and behavioral factors were collected using a structured questionnaire. Active case search and confirmation was done using the Dual Path Platform (DPP) Syphilis Screen and Confirm test kit. Data were analyzed using STATA 15. Logistic regression was done to determine the exposures that were associated with yaws infection at 0.05 significant level.

resultsSixty-two cases and 124 controls were recruited for the study. The adjusted multivariable logistic regression model showed that yaws infection was more likely among individuals who reside in overcrowded compound houses (aOR = 25.42, 95% CI: 6.15-105.09) and with poor handwashing habits (aOR = 6.46, 95% CI: 1.89-22.04). Male (aOR = 4.15, 95% CI: 1.29-13.36) and increasing age (aOR = 5.90, 95% CI: 1.97-17.67) were also associated with yaws infection.

conclusionsPoor personal hygiene, overcrowding and lack of access to improved sanitary facilities are the factors that facilitate the transmission of yaws in the Awutu Senya West and Upper West Akyem districts. Yaws was also more common among males and school-aged children. Improving living conditions, access to good sanitary facilities and encouraging good personal hygiene practices should be core features of eradication programs in endemic communities.

Indexed as

Rural PopulationYawsAdolescentCase-Control StudiesChildChild, PreschoolCrowdingEndemic DiseasesFemaleGhanaHumansHygieneInfantMalePopulation SurveillanceSkin UlcerAwutu Senya westChildrenDual path platformUpper west AkyemYaws

Identifiers

PMID32160927
PMCPMC7066816
OpenAlexW3012433810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.