Evidence map›Paper›PMID 32160876›Full record

Observational studyBMC nephrology2020

Outcomes in acute kidney injury in noncritically ill patients lately referred to nephrologist in a developing country: a comparison of AKIN and KDIGO criteria.

Ginivaldo Victor Ribeiro do Nascimento, Marcela do Nascimento Silva, Juarez Duarte de Carvalho Neto, Ludgero Ribeiro Feitosa Filho, Jessica Duarte Antão

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ginivaldo Victor Ribeiro do NascimentoCentro de Ciências da Saúde - FACIME/UESPI - Coordenação de Medicina, Universidade Estadual do Piauí, Rua Olavo Bilac, 2335, Centro, Teresina, PI, CEP 64001-280, Brazil. gvictor-rn@bol.com.br.
Marcela do Nascimento SilvaFACID/Wyden - Coordenação Medicina, Teresina, Brazil.
Juarez Duarte de Carvalho NetoUninovafapi - Coordenação Medicina, Teresina, Brazil.
Ludgero Ribeiro Feitosa FilhoUninovafapi - Coordenação Medicina, Teresina, Brazil.
Jessica Duarte AntãoFACID/Wyden - Coordenação Medicina, Teresina, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn low-middle-income countries (LMICs), data regarding acute kidney injury (AKI) are scarce. AKI patients experience delayed diagnosis. This study aimed to evaluate whether delayed nephrologist consultation (NC) affected outcomes of AKI patients and compare Acute Kidney Injury Network (AKIN) and Kidney Disease: Improving Global Outcomes (KDIGO).

methodsAn observational, retrospective study was conducted in a tertiary public hospital in an LMIC.

resultsOverall, 103 AKI patients were analysed. In-hospital mortality was 61.16%, and dialysis was required in 38.83%. NC took place after 48 h in 68.93% of the patients. Mean time for NC was 5.22 ± 4.30 days. At NC, serum creatinine was 4.48 (±3.40) mg/dL and blood urea nitrogen was 68.21 (± 35.02) mg/dL. The AKIN and KDIGO stage stratifications were identical; KDIGO stage 3 was seen in 58.25% of the patients. The group with NC >  4 days had a mortality rate of 74.46% and the group with NC ≤ 4 days had a mortality rate of 50% (p = 0.011). Multivariate analysis showed that haemodialysis was independently associated with mortality. NC >  4 days was associated with death [odds ratio 2.66 (95% confidence interval, 1.36-4.35), p = 0.001]. Logistic regression showed an OR of 1.20 (95% CI, 1.05-1.37) (p = 0.008) for each day of delayed NC.

conclusionDelayed NC was associated with mortality even after adjustments, as was haemodialysis, though marginally. In AKI patients with NC > 4 days, there was a high prevalence of KDIGO stage 3, and AKIN and KDIGO criteria were identical.

Indexed as

Delayed DiagnosisDeveloping CountriesReferral and ConsultationSeverity of Illness IndexTime-to-TreatmentAcute Kidney InjuryBlood Urea NitrogenBrazilCreatinineFemaleHumansMaleMiddle AgedNephrologyRegression AnalysisRenal DialysisCreatinineAcute kidney injuryDeveloping countryDialysisNephrologist consultationNephrologist referral

Identifiers

PMID32160876
PMCPMC7066785

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.