ArticleStress (Amsterdam, Netherlands)2021
Validity of the Trier Social Stress Test in studying discrimination stress.
Article in Stress (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Minority stress in relation to biological outcomes among sexual and gender minority people: a systematic review and update.Journal of behavioral medicine · 2025Pooled it
- Social buffering of the cortisol stress response during the Minnesota Imaging Stress Test in Children.Psychoneuroendocrinology · 2026Trial
- Cortisol Stress Response is Associated with Iron Status in Pregnancy.medRxiv : the preprint server for health sciences · 2026Article
- Real-Time Stress Experiences and Physiological and Psychological Responses Among LGBTQ+ Young Adults: Findings from the Stress and Heart Pilot Study.Sensors (Basel, Switzerland) · 2026Article
- Reassessing cardiometabolic health disparities among young adult sexual minority women: Evidence from a population-based cohort.PloS one · 2026Article
- A compassion microintervention targeting stress reactivity among sexual minority women and transgender/nonbinary people: Study protocol for a randomized controlled trial.Contemporary clinical trials · 2024Article
- A meta-analysis of salivary cortisol responses in the Trier Social Stress Test to evaluate the effects of speech topics, sex, and sample size.Comprehensive psychoneuroendocrinology · 2022Article
- Gay men's stress response to a general and a specific social stressor.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
- A Social Affective Neuroscience Model of Risk and Resilience in Adolescent Depression: Preliminary Evidence and Application to Sexual and Gender Minority Adolescents.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Review
- The Relationship Between Perceived Control and Hypothalamic-Pituitary-Adrenal Axis Reactivity to the Trier Social Stress Test in Healthy Young Adults.Frontiers in psychology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
To test the validity of a modified Trier Social Stress Test (TSST) for studying stress reactivity in sexual minority women. Two hundred seventy-four female participants (66.4% Black American), half of whom identified as lesbian/gay or bisexual and half as heterosexual, completed the TSST with instructions to describe an experience of discrimination. Cortisol levels and negative emotion scores increased, and heart rate variability decreased in response to the TSST, and the magnitude of these responses varied as a function of sexual orientation and race. Women who discussed sexual orientation as a source of discrimination had greater increases in cortisol and negative mood following the TSST. The modified instructions did not compromise the validity of the TSST. Prompting participants to discuss specific sources of discrimination may be a useful adaptation of the TSST in studying minority stress reactivity. SUMMARY The goal of the present study was to adapt a widely used measure of stress reactivity to study the impact of experiences with discrimination on biological systems involved in regulating the stress response. The modification included asking women to discuss a time when they had been treated unfairly and to describe how they responded to that experience. The magnitude of response to the task varied as a function of sexual orientation and race, and the topics discussed, demonstrating usefulness of the modification for studying the impact of discrimination stress of physical health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.