Evidence map›Paper›PMID 32160692›Full record

ArticlePsychiatry investigation2020

Neural Mechanisms in Eating Behaviors: A Pilot fMRI Study of Emotional Processing.

Rosa M Molina-Ruiz, T García-Saiz, Jeffrey C L Looi, E Via Virgili, M Rincón Zamorano, Laura de Anta Tejado, Helena Trebbau López, Jose Luis Carrasco Perera, Marina Díaz-Marsá

Open access · diamondAbstract read
In one paragraph

Article in Psychiatry investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Neuromodulation and Eating Disorders.Current psychiatry reports · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Rosa M Molina-RuizPsychiatry Department, Universitary Hospital Clinico San Carlos de Madrid, IddISC, Madrid, Spain.
T García-SaizArtificial Intelligence Department, UNED. E.T.S.I. Informatics, Madrid, Spain.
Jeffrey C L LooiAcademic Unit of Psychiatry and Addiction Medicine, Australian National University Medical School, Canberra Hospital, Canberra, Australia.
E Via VirgiliHospital Materno-Infantil Sant Joan de Déu, Barcelona, Spain.
M Rincón ZamoranoArtificial Intelligence Department, UNED. E.T.S.I. Informatics, Madrid, Spain.
Laura de Anta TejadoPsychiatry Department, Universitary Hospital Clinico San Carlos de Madrid, IddISC, Madrid, Spain.
Helena Trebbau LópezPsychiatry Department, Universitary Hospital Clinico San Carlos de Madrid, IddISC, Madrid, Spain.
Jose Luis Carrasco PereraPsychiatry Department, Universitary Hospital Clinico San Carlos de Madrid, IddISC, Madrid, Spain.
Marina Díaz-MarsáPsychiatry Department, Universitary Hospital Clinico San Carlos de Madrid, IddISC, Madrid, Spain.
Hospital Clínico San Carlos · ESNational University of Distance Education · ESCanberra Hospital · AUHospital Materno-Infantil · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEmotional processing dysfunction evident in eating disorders (ED) such as anorexia nervosa (AN) and bulimia nervosa (BN), is considered relevant to the development and maintenance of these disorders. The purpose of the current functional magnetic resonance imaging (fMRI) study was to pilot a comparison of the activity of the fronto-limbic and fronto-striatal brain areas during an emotion processing task in persons with ED.

methods24 women patients with ED were scanned, while showing emotionally stimulating (pleasant, unpleasant) and neutral images from the International Affective Picture System (IAPS).

resultsDuring the pleasant condition, significant differences in Dorsolateral Prefrontal Cortex (DLPFC) activations were found with AN participants presenting greater activation compared to BN and ED comorbid groups (EDc) and healthy controls also showing greater activation of this brain area compared to BN and EDc. Left putamen was less activated in EDc compared to both controls (C) and AN. During the unpleasant condition, AN participants showed hyperactivation of the Orbito-frontal Cortex (OFC) when compared to EDc.

conclusionThis study highlights the potential functional relevance of brain areas that have been associated with self-control. These findings should help advance understanding the neural substrate of ED, though they should be considered as preliminary and be cautiously interpreted.

Indexed as

Eating disordersEmotion processingFunctional magnetic resonance imagingPrefrontal cortexStriatum

Identifiers

PMID32160692
PMCPMC7113175
OpenAlexW3012034858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.