Evidence map›Paper›PMID 32160565›Full record

ReviewTrends in cognitive sciences2020

Broca's Area Is Not a Natural Kind.

Evelina Fedorenko, Idan A Blank

Registry-linked trialAbstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05222594 (Computational Neuroscience of Language Processing in the Human Brain), which is not on this map. Cited by 156 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05222594 narecruitingnot on this mapstarted 2021, after this paper: background citation

Computational Neuroscience of Language Processing in the Human Brain

TypeinterventionalSponsorMassachusetts General HospitalRan2021 to 2027Enrolled40ConditionsLanguage, EpilepsyArmsBehavioral tasks during intracranial monitoring
3 · Its place in the literature

Who cites it

156 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Review
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  13. The Extended Language Network: Language-Responsive Brain Areas Whose Contributions to Language Remain To Be Discovered.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  18. Premotor cortex uses a compositional neural geometry to plan words.bioRxiv : the preprint server for biology · 2026
    Article
  19. Article
  20. Domain-general demands that deactivate multiple-demand regions.Cerebral cortex (New York, N.Y. : 1991) · 2026
    Article

96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Evelina FedorenkoBrain and Cognitive Sciences Department, and McGovern Institute for Brain Research, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Electronic address: evelina9@mit.edu.
Idan A BlankDepartment of Psychology, University of California at Los Angeles (UCLA), Los Angeles, CA 90095, USA. Electronic address: iblank@mit.edu.

Funding

Functional reorganization of the language and domain-general multiple demand systems in aphasiaR01DC016950 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI FEDORENKO, EVELINA, KIRAN, SWATHI · 2019 to 2023
$3.2M
The neural architecture of pragmatic processingR01DC016607 · NIDCD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI FEDORENKO, EVELINA · 2018 to 2022
$2.4M
fMRI investigations of the functional architecture of the language systemR00HD057522 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI FEDORENKO, EVELINA · 2014 to 2016
$738k
NICHD NIH HHS R00 HD057522NIDCD NIH HHS R01 DC016607NIDCD NIH HHS R01 DC016950
6 · The paper itself

Abstract

Theories of human cognition prominently feature 'Broca's area', which causally contributes to a myriad of mental functions. However, Broca's area is not a monolithic, multipurpose unit - it is structurally and functionally heterogeneous. Some functions engaging (subsets of) this area share neurocognitive resources, whereas others rely on separable circuits. A decade of converging evidence has now illuminated a fundamental distinction between two subregions of Broca's area that likely play computationally distinct roles in cognition: one belongs to the domain-specific 'language network', the other to the domain-general 'multiple-demand (MD) network'. Claims about Broca's area should be (re)cast in terms of these (and other, as yet undetermined) functional components, to establish a cumulative research enterprise where empirical findings can be replicated and theoretical proposals can be meaningfully compared and falsified.

Indexed as

Broca AreaMagnetic Resonance ImagingBrain MappingCognitionFrontal LobeHumansLanguagearticulationBroca’s areadomain-specificityexecutive functionslanguageLIFG

Identifiers

PMID32160565
PMCPMC7211504

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.