ArticleCell reports2020
Neurokinin-1 Receptor Signaling Is Required for Efficient Ca
Open access · goldAbstract read
In one paragraph
Article in Cell reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- Neuroimmune circuits in respiratory pathophysiology: decoding molecular crosstalk for precision therapeutic targeting.Annals of medicine · 2026Review
- Neuroimmune Regulation in Posttraumatic Bone Repair: From Inflammatory Transition to Neurovascular Coupling and Functional Recovery.Journal of cellular physiology · 2026Review
- The role of substance P in Th17/Treg imbalance and ocular surface damage in chronic allergic conjunctivitis.Journal of translational medicine · 2025Article
- The role of the enteric nervous system in the pathogenesis of Clostridioides difficile infection.Nature reviews. Gastroenterology & hepatology · 2025Review
- Substance P receptor signaling contributes to host maladaptive responses during enteric bacterial infection.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Contemporary insights into neuroimmune interactions across development and aging.Frontiers in neurology · 2025Review
- Substance P receptor signaling contributes to host maladaptive responses during enteric bacterial infection.bioRxiv : the preprint server for biology · 2024Article
- From pain to tumor immunity: influence of peripheral sensory neurons in cancer.Frontiers in immunology · 2024Review
- IFN-γ-STAT1-mediated NK2R expression is involved in the induction of antitumor effector CD8Cancer science · 2023Article
- Neuroimmune communication in allergic rhinitis.Frontiers in neurology · 2023Review
- Immunomodulatory Role of Neuropeptides in the Cornea.Biomedicines · 2022Review
- Skin codelivery of contact sensitizers and neurokinin-1 receptor antagonists integrated in microneedle arrays suppresses allergic contact dermatitis.The Journal of allergy and clinical immunology · 2022Article
- Botulinum Toxin Use for Modulating Neuroimmune Cutaneous Activity in Psoriasis.Medicina (Kaunas, Lithuania) · 2022Review
- Neuroimmune regulatory networks of the airway mucosa in allergic inflammatory disease.Journal of leukocyte biology · 2022Review
- Structures of neurokinin 1 receptor in complex with GScience advances · 2021Article
- The Role of Neuropeptides in Pathogenesis of Dry Dye.Journal of clinical medicine · 2021Review
- Peripheral neuroimmune interactions: selected review and some clinical implications.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Review
- Neuroimmune Pathophysiology in Asthma.Frontiers in cell and developmental biology · 2021Review
- Neurokinin receptors and their implications in various autoimmune diseases.Current research in immunology · 2021Review
- Involvement of Neuro-Immune Interactions in Pruritus With Special Focus on Receptor Expressions.Frontiers in medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 4 countries.
Adrian E MorelliThomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA; Department of Surgery, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA; Department of Immunology, University of Pittsburgh, School of Medicine Pittsburgh, PA, USA.
Tina L SumpterDepartment of Immunology, University of Pittsburgh, School of Medicine Pittsburgh, PA, USA; Department of Dermatology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.
Darling M Rojas-CanalesFlinders University, College of Medicine and Public Health, Adelaide, SA, Australia.
Mohna BandyopadhyayDepartment of Dermatology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.
Zhizhao ChenHubei Key Laboratory of Medical Technology on Transplantation, Transplant Center, Institute of Hepatobiliary Diseases, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Olga TkachevaDepartment of Dermatology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.
William J ShufeskyThomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA; Department of Surgery, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.
Callen T WallaceDepartment of Cell Biology and Center for Biological Imaging, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA; The McGowan Center for Regenerative Medicine, Pittsburgh, PA, USA.
Simon C WatkinsDepartment of Immunology, University of Pittsburgh, School of Medicine Pittsburgh, PA, USA; Department of Cell Biology and Center for Biological Imaging, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA; The McGowan Center for Regenerative Medicine, Pittsburgh, PA, USA.
Alexandra BergerOntario Cancer Institute, Princess Margaret Hospital, Toronto, ON, Canada.
Christopher J PaigeOntario Cancer Institute, Princess Margaret Hospital, Toronto, ON, Canada.
Louis D FaloDepartment of Dermatology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA; The McGowan Center for Regenerative Medicine, Pittsburgh, PA, USA; Department of Bioengineering, University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA, USA; The University of Pittsburgh Clinical and Translational Science Institute, Pittsburgh, PA, USA; The UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Adriana T LarreginaDepartment of Immunology, University of Pittsburgh, School of Medicine Pittsburgh, PA, USA; Department of Dermatology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA; The McGowan Center for Regenerative Medicine, Pittsburgh, PA, USA. Electronic address: adrianal@pitt.edu.
University of Pittsburgh · USOntario Institute for Cancer Research · CAFlinders University · AUWuhan University · CN
Funding
Engineering the Skin Microenvironment to Promote Allergen ToleranceR01AR074285 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FALO, LOUIS D, LITTLE, STEVEN R · 2018 to 2023
$3.0MPlacental extracellular vesicles as regulators of maternal adaptive immunityR01AI148690 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MORELLI, ADRIAN E., SADOVSKY, YOEL · 2019 to 2023
$2.7MMNA Delivery of Neurokinin 1 Receptor Antagonists to Treat Atopic DermatitisR01AR071277 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FALO, LOUIS D, LARREGINA, ADRIANA T · 2017 to 2021
$2.4MManipulating Cutaneous Neuroimmunity to Treat Contact DermatitisR01AR068249 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FALO, LOUIS D, LARREGINA, ADRIANA T · 2015 to 2019
$2.1MHL Exosomes as paracrine signal mediators in cardiac allograft rejectionR01HL130191 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MORELLI, ADRIAN E. · 2016 to 2019
$1.5MManipulating Neuropeptide Receptors in Mast Cells for Atopic Dermatitis TreatmentK01AR067250 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SUMPTER, TINA L · 2015 to 2019
$437kCIHR 9862NHLBI NIH HHS R01 HL130191NIAID NIH HHS R01 AI148690NIAMS NIH HHS K01 AR067250NIAMS NIH HHS R01 AR068249NIAMS NIH HHS R01 AR071277NIAMS NIH HHS R01 AR074285
Abstract
Efficient Ca
Indexed as
Signal TransductionAnimalsAutocrine CommunicationCalciumCD4-Positive T-LymphocytesCell PolarityCell SurvivalImmunological SynapsesInterleukin-2Lymphocyte ActivationMiceNF-kappa BReceptors, Antigen, T-CellReceptors, Neurokinin-1Substance PTachykininsCalciumhemokinin-1Interleukin-2NF-kappa BReceptors, Antigen, T-CellReceptors, Neurokinin-1Substance PTachykininsCa(2+) fluxG-protein-coupled receptorsG(αq/11)hemokinin-1neurokinin-1 receptorsubstance PT cell activationT cell biasT cell receptorT cell survival
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.