Evidence map›Paper›PMID 32160414›Full record

ArticleFEBS open bio2020

Thioredoxin mitigates H

Meiling Liu, Xianglu Li, Changlin Zhou, Manfeng Wang, Hongzhi Wang, Haifeng Ding, Luyang Cheng, Lu Gan, Xiaowei Wu, Zhimin Du

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS open bio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Meiling LiuDepartment of Geriatrics, The Second Affiliated Hospital of Harbin Medical University, China.
Xianglu LiDepartment of Geriatrics, The Second Affiliated Hospital of Harbin Medical University, China.
Changlin ZhouDepartment of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, China.
Manfeng WangDepartment of Geriatrics, The Second Affiliated Hospital of Harbin Medical University, China.
Hongzhi WangDepartment of Geriatrics, The Second Affiliated Hospital of Harbin Medical University, China.
Haifeng DingDepartment of Geriatrics, The Second Affiliated Hospital of Harbin Medical University, China.
Luyang ChengDepartment of Geriatrics, The Second Affiliated Hospital of Harbin Medical University, China.
Lu GanDepartment of Geriatrics, The Second Affiliated Hospital of Harbin Medical University, China.
Xiaowei WuDepartment of Geriatrics, The Second Affiliated Hospital of Harbin Medical University, China.ORCID 0000-0001-9012-9841
Zhimin DuInstitute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University, China.
Harbin Medical University · CNMacau University of Science and Technology · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thioredoxin (Trx) is a hydrogen acceptor of ribonucleotide reductase and a regulator of some enzymes and receptors. It has been previously shown that significantly elevated levels of Trx expression are associated with the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), but it is not clear how Trx regulates the effects of hydrogen peroxide (H

Indexed as

AnimalsAntioxidantsBone Marrow CellsCell DifferentiationCell SurvivalChinaGlutathione PeroxidaseHydrogen PeroxideMaleMesenchymal Stem CellsMuscle DevelopmentOxidative StressProto-Oncogene Proteins c-aktRatsRats, Sprague-DawleyReactive Oxygen SpeciesAntioxidantsGlutathione PeroxidaseHydrogen PeroxideProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSuperoxide DismutaseThioredoxinsAktbone marrow mesenchymal stem cellshuman recombinant thioredoxinhydrogen peroxidemyogenic differentiationthioredoxin

Identifiers

PMID32160414
PMCPMC7193161
OpenAlexW3011251630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.