Evidence map›Paper›PMID 32159278›Full record

ReviewPediatric blood & cancer2020

Psychosocial care for children receiving chimeric antigen receptor (CAR) T-cell therapy.

Angela Steineck, Lori Wiener, Jennifer W Mack, Nirali N Shah, Corinne Summers, Abby R Rosenberg

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric blood & cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Angela SteineckCancer and Blood Disorders Center, Seattle Children's Hospital, Seattle, Washington.ORCID 0000-0002-8000-0179
Lori WienerCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0002-9573-8870
Jennifer W MackDana Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0001-5791-4178
Nirali N ShahCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0002-8474-9080
Corinne SummersCancer and Blood Disorders Center, Seattle Children's Hospital, Seattle, Washington.
Abby R RosenbergCancer and Blood Disorders Center, Seattle Children's Hospital, Seattle, Washington.ORCID 0000-0002-7608-607X
Seattle Children's Hospital · USNational Institutes of Health · USHarvard University · US

Funding

Pediatric Oncology Branch Behvioral Science CoreZIDBC011517 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GLOD, JOHN · 2013 to 2025
$15.6M
PEDIATRIC ONCOLOGY RESEARCH TRAINING PROGRAMT32CA009351 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth R Lawlor, SOHEIL MESHINCHI · 1985 to 2026
$7.0M
NCI NIH HHS L40 CA253025NCI NIH HHS T32 CA009351NIH HHS 5T32CA009351-40
6 · The paper itself

Abstract

Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia (ALL). However, this new paradigm has introduced unique considerations specific to the patients receiving CAR T-cell therapy, including prognostic uncertainty, symptom management, and psychosocial support. With increasing availability, there is a growing need for evidence-based recommendations that address the specific psychosocial needs of the children who receive CAR T-cell therapy and their families. To guide and standardize the psychosocial care offered for patients receiving CAR T-cell therapy, we propose the following recommendations for addressing psychosocial support.

Indexed as

Receptors, Chimeric AntigenChildHumansImmunotherapy, AdoptivePrecursor B-Cell Lymphoblastic Leukemia-LymphomaReceptors, Chimeric Antigenacute lymphoblastic leukemiachimeric antigen receptor t-cellcommunicationinterdisciplinary carepalliative carepediatric oncologypsychosocialsymptom management

Identifiers

PMID32159278
PMCPMC8396063
OpenAlexW3011916699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.