Evidence map›Paper›PMID 32159165›Full record

ArticleThe Analyst2020

Rapid, quantitative therapeutic screening for Alzheimer's enzymes enabled by optimal signal transduction with transistors.

Son T Le, Michelle A Morris, Antonio Cardone, Nicholas B Guros, Jeffery B Klauda, Brent A Sperling, Curt A Richter, Harish C Pant, Arvind Balijepalli

Open access · greenAbstract read
In one paragraph

Article in The Analyst, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Son T LeAlternative Computing Group, Nanoscale Device Characterization Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA.
Michelle A Morris
Antonio Cardone
Nicholas B Guros
Jeffery B Klauda
Brent A Sperling
Curt A Richter
Harish C Pant
Arvind Balijepalli
National Institute of Standards and Technology · USNational Institutes of Health · USPark University · US

Funding

Role of a novel neuropeptide (p5/Tp5/TFp5) derived from a neuronal cell cycle kinase (Cdk5),p35 activator protein, in neurobiologyZIANS002725 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI PANT, HARISH C · 2009 to 2020
$9.6M
Intramural NIST DOC 9999-NIST
6 · The paper itself

Abstract

We show that commercially sourced n-channel silicon field-effect transistors (nFETs) operating above their threshold voltage with closed loop feedback to maintain a constant channel current allow a pH readout resolution of (7.2 ± 0.3) × 10

Indexed as

Transistors, ElectronicAlzheimer DiseaseCyclin-Dependent Kinase 5Electrochemical TechniquesHumansHydrogen-Ion ConcentrationNeuroprotective AgentsPeptidesSiliconCDK5 protein, humanCyclin-Dependent Kinase 5Neuroprotective AgentsPeptidesSiliconTFP5 peptide

Identifiers

PMID32159165
PMCPMC7443690
OpenAlexW3010450126

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.