ArticleMaterials today. Bio2019
Honeycomb blocks composed of carbonate apatite, β-tricalcium phosphate, and hydroxyapatite for bone regeneration: effects of composition on biological responses.
Article in Materials today. Bio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- A systematic review of a novel alloplast carbonate apatite granules.Frontiers in dental medicine · 2024Pooled it
- Periodontal regenerative therapy using recombinant human fibroblast growth factor (rhFGF)-2 in combination with carbonate apatite granules or rhFGF-2 alone: 12-month randomized controlled trial.Clinical oral investigations · 2024Trial
- Fabrication of Biphasic Hydroxyapatite/Calcium Sulfate Blocks via Hydrothermal Partial Phase Transformation for Bone Substitutes.European journal of dentistry · 2026Article
- Evaluation of the composite materials mixed with calcium phosphate cement and β-tricalcium phosphate granules.International journal of implant dentistry · 2026Article
- Compositionally Optimized Bone Scaffolds Based on Carbonate Apatite and Silver Phosphate for Osteogenesis, Scaffold Resorption, and Photoactivated Antibacterial Activity.ACS applied bio materials · 2025Article
- Strategic Uniaxial Macropore Sizing for Honeycomb-Structured Scaffolds for Enhanced Bone Reconstruction in Segmental Bone Defects.ACS omega · 2025Article
- Effects of Carbonate Apatite and Bone Mixture on Bone and Soft Tissue Integration in a Rat Implant Model.Clinical implant dentistry and related research · 2025Article
- Mechanochemically-Activated Solid-State Synthesis of Borate-Substituted Tricalcium Phosphate: Evaluation of Biocompatibility and Antimicrobial Performance.Molecules (Basel, Switzerland) · 2025Article
- Integrating Micro- and Nanostructured Platforms and Biological Drugs to Enhance Biomaterial-Based Bone Regeneration Strategies.Biomacromolecules · 2025Review
- Three-dimensional-printed strontium-incorporated β-TCP bioceramic triply periodic minimal surface scaffolds with enhanced angiogenic and osteogenic properties.Regenerative biomaterials · 2025Article
- Preferred Orientation of Hydroxyapatite Ceramics Along theInternational journal of molecular sciences · 2024Article
- Carbonate Apatite Honeycomb Scaffold-Based Drug Delivery System for Repairing Osteoporotic Bone Defects.ACS applied materials & interfaces · 2024Article
- Silver phosphate-modified carbonate apatite honeycomb scaffolds for anti-infective and pigmentation-free bone tissue engineering.Materials today. Bio · 2024Article
- Biological Properties and Medical Applications of Carbonate Apatite: A Systematic Review.Pharmaceutics · 2024Review
- 3D-printed tri-element-doped hydroxyapatite/ polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone regeneration.Bioactive materials · 2024Article
- Effects of Space Dimensionality within Scaffold for Bone Regeneration with Large and Oriented Blood Vessels.Materials (Basel, Switzerland) · 2023Article
- Collagen type I-based recombinant peptide promotes bone regeneration in rat critical-size calvarial defects by enhancing osteoclast activity at late stages of healing.Regenerative therapy · 2023Article
- Reconstruction of Load-Bearing Segmental Bone Defects Using Carbonate Apatite Honeycomb Blocks.ACS materials Au · 2023Article
- Effects of combined application of fibroblast growth factor (FGF)-2 and carbonate apatite for tissue regeneration in a beagle dog model of one-wall periodontal defect.Regenerative therapy · 2023Article
- Bone Apatite Nanocrystal: Crystalline Structure, Chemical Composition, and Architecture.Biomimetics (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic scaffolds exhibiting bone repair ability equal to that of autogenous bone are required in the fields of orthopedics and dentistry. A suitable synthetic bone graft substitute should induce osteogenic differentiation of mesenchymal stem cells, osteogenesis, and angiogenesis. In this study, three types of honeycomb blocks (HCBs), composed of hydroxyapatite (HAp), β-tricalcium phosphate (TCP), and carbonate apatite (CO
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.