Evidence map›Paper›PMID 32158748›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Response of Human Macrophages to Clinically Applied Wound Dressings Loaded With Silver.

Patrícia Varela, Lennart Marlinghaus, Susanna Sartori, Richard Viebahn, Jochen Salber, Gianluca Ciardelli

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Patrícia VarelaDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Lennart MarlinghausDepartment of Medical Microbiology, Ruhr-University Bochum, Bochum, Germany.
Susanna SartoriDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Richard ViebahnDepartment of Experimental Surgery, Universitätsklinikum Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, Bochum, Germany.
Jochen SalberDepartment of Experimental Surgery, Universitätsklinikum Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, Bochum, Germany.
Gianluca CiardelliDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Polytechnic University of Turin · ITRuhr University Bochum · DEUniversitätsklinikum Knappschaftskrankenhaus Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound infections constitute an increasing clinical problem worldwide. To reverse this trend, several wound dressings with antimicrobial properties have been developed. Considering the increasing presence of antibiotic-resistant microorganisms, product developers have been focusing their efforts in introducing antibiotic-free antibacterial wound dressings to the market, with silver being the most commonly incorporated antimicrobial agent. In this scenario, gaining information about the microbial and eukaryotic cells' response to these dressings is needed for a proper selection of antimicrobial dressings for the different cases of infected wounds. In particular, one insufficiently explored parameter is the effect of the dressings on the immunomodulation of macrophages, the main immune cell population participating in the repair process, because of their pivotal role in the transition of the inflammation to the proliferation phase of wound healing. In this work, three different clinically applied antimicrobial, silver impregnated wound dressings were selected: Atrauman

Indexed as

immunomodulationmacrophagessilverwound dressingswound infections

Identifiers

PMID32158748
PMCPMC7051918
OpenAlexW3008232458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.