ArticleFrontiers in cellular and infection microbiology2020
Gut Microbiome Profiles Are Associated With Type 2 Diabetes in Urban Africans.
Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
113 citing papers in PubMed, 5 syntheses or guidelines pooled it, 153 citations in OpenAlex.
- Gut microbiota and type 2 diabetes associations: a meta-analysis of 16S studies and their methodological challenges.Frontiers in microbiomes · 2025Pooled it
- Implication of taxonomic abundance of gut microbiota in prediabetes: a systematic review.Frontiers in nutrition · 2025Pooled it
- A systematic review on gut microbiota in type 2 diabetes mellitus.Frontiers in endocrinology · 2024Pooled it
- Pooled it
- Urbanization gradient, diet, and gut microbiota in Sub-Saharan Africa: a systematic review.Frontiers in microbiomes · 2023Pooled it
- Food- vs. supplement-based very-low-energy diets and gut microbiome composition in women with high body mass index: A randomized controlled trial.Cell reports. Medicine · 2025Trial
- Targeting gut microbiota with short-chain fructo-oligosaccharides prebiotic fibers to support metabolic health in overweight prediabetic adults: a randomized, double-blinded, placebo-controlled study.Frontiers in nutrition · 2025Trial
- Impact of Combined Prebiotic Galacto-Oligosaccharides andNutrients · 2024Trial
- Treatment With Multi-Species Probiotics Changes the Functions, Not the Composition of Gut Microbiota in Postmenopausal Women With Obesity: A Randomized, Double-Blind, Placebo-Controlled Study.Frontiers in cellular and infection microbiology · 2022Trial
- The Gut Microbiota-Astrocyte Axis: New Insights into the Mechanisms of Comorbid Major Depressive Disorder in Type 2 Diabetes Mellitus.Molecular neurobiology · 2026Review
- The relationships between figure rating scale, anthropometric measures, and cardiometabolic outcomes: the AADM study.Diabetes & metabolic syndrome · 2026Article
- Butyrate and Butyrate-Producing Bacteria in Cardiovascular-Kidney-Metabolic Syndrome.Antioxidants (Basel, Switzerland) · 2026Review
- Gut microbiome composition and functional potential associate with incident type 2 diabetes in 4,685 adults from a Swedish prospective cohort.Cell reports. Medicine · 2026Article
- Exercise reprograms the gut microbiota to enhance metabolic outcomes after bariatric surgery: a translational, cross-species study.International journal of obesity (2005) · 2026Article
- Impact of a Mediterranean Diet Supplemented with Extra Virgin Olive Oil on Gut Microbiota in Fibromyalgia: A Randomized Controlled Trial.Life (Basel, Switzerland) · 2026Article
- Associations of the gut microbiome and cardiometabolic risk in adolescence: the HOME study.BMC medical genomics · 2026Article
- Gut Microbiome Signatures Distinguish Susceptibility from Disease Development in Type 2 Diabetes.International journal of molecular sciences · 2026Article
- Role of Gut Microbiota in Bridging Vitamin D Deficiency and Type 2 Diabetes Mellitus Pathogenesis.Microorganisms · 2026Review
- Gut microbiota drives the metabolic dysregulation in obesity-prone individuals by impairing GDCA-mediated activation of brown adipose thermogenesis and ileal GLP-1 secretion.Acta pharmaceutica Sinica. B · 2026Article
- Review
53 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Gut dysbiosis has been associated with several disease outcomes including diabetes in human populations. Currently, there are no studies of the gut microbiome composition in relation to type 2 diabetes (T2D) in Africans. Here, we describe the profile of the gut microbiome in non-diabetic adults (controls) and investigate the association between gut microbiota and T2D in urban West Africans. Gut microbiota composition was determined in 291 Nigerians (98 cases, 193 controls) using fecal 16S V4 rRNA gene sequencing done on the Illumina MiSeq platform. Data analysis of operational taxonomic units (OTU) was conducted to describe microbiome composition and identify differences between T2D and controls. The most abundant phyla were
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.