ReviewDrugs in context2019
Motion sickness: an overview.
Review in Drugs in context, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Investigation of Heart Rate Variability Indices in Motion Sickness.Sensors (Basel, Switzerland) · 2026Pooled it
- Antihistamines for motion sickness.The Cochrane database of systematic reviews · 2022Pooled it
- Exploring the Evolving Role of Scopolamine in Pharmacotherapy: From Cognitive Impairment to Neuroplasticity?-A Narrative Review.Molecules (Basel, Switzerland) · 2026Review
- Electrospun PLA/PVP K90 Biphasic-Release Sublingual Film for Motion Sickness Treatment.Biomolecules · 2026Article
- Motion Sickness, Binocular Visual Functions, and Visual Perception.Journal of clinical medicine · 2026Article
- Article
- Postoperative nausea and vomiting: current concepts, management strategies, and future perspectives.Frontiers in pharmacology · 2026Review
- The gut feeling in motion sickness.Communications biology · 2025Review
- Preparation and evaluation of immediate and modified release tablets contained diphenidol hydrochloride.Scientific reports · 2025Article
- Ear, nose and throat disorders and international travel.Tropical diseases, travel medicine and vaccines · 2025Review
- Preparation, characterization, and in vitro cytogenotoxic evaluation of a novel dimenhydrinate-β-cyclodextrin inclusion complex.Biomolecules & biomedicine · 2024Article
- Neuro-ophthalmic and Neuro-otologic Evaluation in Individuals with Motion Sickness Susceptibility.The journal of international advanced otology · 2024Article
- Relationship Between Motion Sickness Susceptibility and Vestibular Test Results.Medeniyet medical journal · 2024Article
- Incidence and Importance of Peripheral Vestibular Dysfunction in Adolescent Idiopathic Scoliosis.Children (Basel, Switzerland) · 2024Article
- Development and Evaluation of Vibration Canceling System Utilizing Macro-Fiber Composites (MFCs) and Long Short-Term Memory (LSTM) Vibration Prediction AI Algorithms for Road Driving Vibrations.Materials (Basel, Switzerland) · 2024Article
- Using a Virtual Reality Tool to Provide Primary Prevention Training in the Construction Field Following a Periodic Medical Visit: Cross-Sectional Study.JMIR serious games · 2024Article
- Psychometric properties of the Turkish version of the Vestibular Migraine Patient Assessment Tool and Handicap Inventory.Turkish journal of medical sciences · 2024Article
- Development of a new immersive virtual reality (VR) headset-based dexterity training for patients with multiple sclerosis: Clinical and technical aspects.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Evaluating proxies for motion sickness in rodent.IBRO neuroscience reports · 2023Article
- Nutritional and Behavioral Countermeasures as Medication Approaches to Relieve Motion Sickness: A Comprehensive Review.Nutrients · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMotion sickness is a common phenomenon that affects almost everybody at some point in their lifetime. Clinicians should be familiar with the proper management of this condition.
objectiveTo provide an update on the current understanding of the pathophysiology and management of motion sickness.
methodsA PubMed search was performed with Clinical Queries using the key term 'motion sickness.' The search strategy included meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews. The search was restricted to English literature. The information retrieved from the earlier search was used in the compilation of the present article.
resultsMotion sickness is typically triggered by low-frequency vertical, lateral, angular, rotary motion, or virtual stimulator motion, to which an individual has not adapted.
conclusionIn most cases, motion sickness can be prevented by behavioral and environmental modifications (avoidance, habituation, and minimization of motion stimuli). Pharmacotherapy should be considered in the prevention and/or treatment of more severe motion sickness and for patients who do not respond to conservative measures. Medications are most effective when combined with behavioral and environmental modifications. Drugs that are effective in the prophylaxis and/or treatment of motion sickness include anticholinergic agents and antihistamines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.