Evidence map›Paper›PMID 32158053›Full record

ReviewMissouri medicine

The Benefits of Omega-3 Fats for Stabilizing and Remodeling Atherosclerosis.

James J DiNicolantonio, James H O'Keefe

Abstract readReview
In one paragraph

Review in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

James J DiNicolantonioJames J. DiNicolantonio, PharmD, and James H. O'Keefe, MD, MSMA member since 2003, are at Saint Luke's Mid America Heart Institute, Kansas City, Missouri.
James H O'KeefeJames J. DiNicolantonio, PharmD, and James H. O'Keefe, MD, MSMA member since 2003, are at Saint Luke's Mid America Heart Institute, Kansas City, Missouri.
Saint Luke's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of acute coronary syndromes are caused by the rupture of plaques rendered vulnerable by oxidized lipids, inflammation, and a thin fibrous cap with reduced collagen and smooth muscle cell content.2 Thus, stabilizing and reversing vulnerable atherosclerotic plaques can help to prevent cardiovascular events. In this regard, long-chain omega-3 fatty acids have a plethora of data for stabilizing vulnerable atherosclerotic plaques as well as reversing atherosclerosis. This review paper will summarize the observational data as well as animal and human studies supporting such a role and further discuss the current controversies around omega-3 supplementation.

Indexed as

Dietary SupplementsAnimalsAtherosclerosisCardiovascular DiseasesDisease Models, AnimalFatty Acids, Omega-3HumansRandomized Controlled Trials as TopicFatty Acids, Omega-3

Identifiers

PMID32158053
PMCPMC7023944
OpenAlexW3014029245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.