Evidence map›Paper›PMID 32158048›Full record

ReviewMissouri medicine

Image Guidance in Cranial Neurosurgery: How a Six-Ton Magnet and Fluorescent Colors Make Brain Tumor Surgery Better.

Michael R Chicoine, Peter Sylvester, Alexander T Yahanda, Amar Shah

Abstract readReview
PubMed Full text at PMC
In one paragraph

Review in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael R ChicoineMichael R. Chicoine, MD, is the August A. Busch, Jr. Professor of Neurological Surgery; Peter Sylvester, MD, Neurosurgery Resident PGY6; Alexander T. Yahanda, BS; and Amar Shah, MD, are all in the Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri.
Peter SylvesterMichael R. Chicoine, MD, is the August A. Busch, Jr. Professor of Neurological Surgery; Peter Sylvester, MD, Neurosurgery Resident PGY6; Alexander T. Yahanda, BS; and Amar Shah, MD, are all in the Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri.
Alexander T YahandaMichael R. Chicoine, MD, is the August A. Busch, Jr. Professor of Neurological Surgery; Peter Sylvester, MD, Neurosurgery Resident PGY6; Alexander T. Yahanda, BS; and Amar Shah, MD, are all in the Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri.
Amar ShahMichael R. Chicoine, MD, is the August A. Busch, Jr. Professor of Neurological Surgery; Peter Sylvester, MD, Neurosurgery Resident PGY6; Alexander T. Yahanda, BS; and Amar Shah, MD, are all in the Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri.
University of Mary · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maximal safe resection can improve patient outcomes for a variety of brain tumor types including low- and high-grade gliomas, pituitary adenomas, and other pathologies. Numerous intraoperative adjuncts exist to guide surgeons with maximizing extent of resection. Three distinct strategies exist including: 1) surgical navigation; 2) intraoperative imaging; and 3) tumor fluorescence. Surgical navigation involves registration of high-resolution three-dimensional imaging to the patient's cranial surface anatomy, allowing real-time localization of tumor and brain structures. Intraoperative imaging devices like intraoperative magnetic resonance imaging (iMRI), intraoperative computed tomography (iCT), 3-D fluoroscopy, and intraoperative ultrasonography (iUS) allow near real time visualization to assess the extent of resection. Intraoperative fluorescence via intravenous fluorescein or oral 5-aminolevulinic acid (5-ALA) causes brain tumors to "light up", which can be viewed through surgical optics using selective filters and specific wavelength light sources. A general overview, as well as implementation and utilization of some of these image guidance strategies at Washington University and by Siteman Cancer Center neurosurgeons at Barnes Jewish Hospital, is discussed in this review.

Indexed as

Aminolevulinic AcidBrainBrain NeoplasmsGliomaHumansImaging, Three-DimensionalMagnetic Resonance ImagingNeurosurgical ProceduresPhotosensitizing AgentsSurgery, Computer-AssistedTomography, X-Ray ComputedAminolevulinic AcidPhotosensitizing Agents

Identifiers

PMID32158048
PMCPMC7023946
OpenAlexW3013033275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.