Evidence map›Paper›PMID 32157988›Full record

ArticleBJPsych open2020

Community perceptions of barriers to management of chronic psychotic disorders and knowledge and attitudes about long-acting injectable antipsychotic medication: qualitative study in Dar es Salaam, Tanzania.

Carol Blixen, Isaac Lema, Jessie Mbwambo, Sylvia Kaaya, Jennifer B Levin, Martha Sajatovic

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Carol BlixenDepartment of Psychiatry and Neurological and Behavioral Outcomes Center, Case Western Reserve University School of Medicine, USA.
Isaac LemaDepartment of Psychiatry and Mental Health, Muhimbili University of Health and Allied Sciences, School of Medicine, Tanzania.
Jessie MbwamboDepartment of Psychiatry and Mental Health, Muhimbili University of Health and Allied Sciences, School of Medicine, Tanzania.
Sylvia KaayaDepartment of Psychiatry and Mental Health, Muhimbili University of Health and Allied Sciences, School of Medicine, Tanzania.
Jennifer B LevinDepartment of Psychiatry and Neurological & Behavioral Outcomes Center, Case Western Reserve University School of Medicine, and University Hospitals Cleveland Medical Center, USA.
Martha SajatovicDepartment of Psychiatry and Neurological and Behavioral Outcomes Center, Case Western Reserve University School of Medicine, USA.ORCID https://orcid.org/0000-0002-3073-668X
Muhimbili University of Health and Allied Sciences · TZCase Western Reserve University · USUniversity Hospitals of Cleveland · US

Funding

Reducing the Burden of Chronic Psychotic Disorders in TanzaniaR21MH114700 · NIMH · CASE WESTERN RESERVE UNIVERSITY · PI MBWAMBO, JESSIE K, SAJATOVIC, MARTHA X · 2017 to 2018
$348k
NIMH NIH HHS R21 MH114700
6 · The paper itself

Abstract

backgroundLow- and middle-income countries (LMICs) experience a disproportionate burden from chronic psychotic disorders (CPDs), which are the most disabling conditions among people aged 10-24 in Sub-Saharan Africa. Poor medication adherence is seen in approximately half of individuals with CPDs in Sub-Saharan Africa, and is a major driver of relapse. A CPD treatment approach that combines the use of long-acting injectable (LAI) antipsychotic medications with a brief and practical customised adherence-enhancement behavioural intervention (CAE-L) was recently developed and tested for use in the USA.

aimsTo use a qualitative cross-sectional analysis to gather information on potentially modifiable barriers to management of CPDs, and assess attitudes about LAIs from community participants in Tanzania. Findings were intended to refine the CAE-L curriculum for use in Tanzania.

methodIn-depth interviews and focus groups were conducted with 44 participants (patients with CPD, caregivers, mental healthcare providers). All interviews and focus groups were audiotaped, translated, transcribed and analysed using content analysis, with an emphasis on dominant themes.

resultsFindings indicated that promoting medication adherence and management of CPDs in the Tanzanian setting needs to consider the individual with CPD, the family, the healthcare setting and the broader community context.

conclusionsQualitative findings enabled the study team to better understand the real-time barriers to medication adherence, LAI use and management of CPDs more broadly. Refinement of the CAE-L is expected to pave the way for an intervention trial for individuals with CPDs that is culturally and linguistically appropriate to the Tanzanian setting.

Indexed as

adherencelong acting injectable (LAI)Low and middle income countriespsychotic disordersstigma and discrimination

Identifiers

PMID32157988
PMCPMC7176827
OpenAlexW3010756851

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.