Evidence map›Paper›PMID 32157643›Full record

ReviewHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2020

Hyperuricemia and Risk of Cardiovascular Outcomes: The Experience of the URRAH (Uric Acid Right for Heart Health) Project.

Alessandro Maloberti, C Giannattasio, M Bombelli, G Desideri, A F G Cicero, M L Muiesan, E A Rosei, M Salvetti, A Ungar, G Rivasi and 32 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 147 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Review
  14. Article
  15. Observational
  16. Hyperuricemia in Cardiac Rehabilitation Patients: Prevalence and Association with Functional Improvement and Left Ventricular Ejection Fraction.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
  17. Review
  18. High serum uric acid is a risk factor for arterial stiffness in a Chinese hypertensive population: a cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 19 institutions in 1 country.

Alessandro MalobertiCardiology IV, "A.De Gasperis" Department, Ospedale Niguarda Ca' Granda, Piazza Ospedale Maggiore 3, 20159, Milan, Italy. alessandro.maloberti@ospedaleniguarda.it.
C GiannattasioCardiology IV, "A.De Gasperis" Department, Ospedale Niguarda Ca' Granda, Piazza Ospedale Maggiore 3, 20159, Milan, Italy.
M BombelliHealth Science Department, Milano-Bicocca University, Milan, Italy.
G DesideriDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
A F G CiceroDepartment of Medical and Surgical Science, Alma Mater Studiorum University of Bologna, Bologna, Italy.
M L MuiesanDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
E A RoseiDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
M SalvettiDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
A UngarDepartment of Geriatric and Intensive Care Medicine, Careggi Hospital and University of Florence, Florence, Italy.
G RivasiDepartment of Geriatric and Intensive Care Medicine, Careggi Hospital and University of Florence, Florence, Italy.
R PontremoliDepartment of Internal Medicine, University of Genoa and Policlinico SanMartino, Genoa, Italy.
F ViazziDepartment of Internal Medicine, University of Genoa and Policlinico SanMartino, Genoa, Italy.
R FacchettiHealth Science Department, Milano-Bicocca University, Milan, Italy.
C FerriDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
B BernardinoDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
F GallettiDepartment of Clinical Medicine and Surgery, "Federico II" University of Naples Medical School, Naples, Italy.
L D'EliaDepartment of Clinical Medicine and Surgery, "Federico II" University of Naples Medical School, Naples, Italy.
P PalatiniStudium Patavinum, Department of Medicine, University of Padua, Padua, Italy.
E CasigliaStudium Patavinum, Department of Medicine, University of Padua, Padua, Italy.
V TikhonoffDepartment of Medicine, University of Padua, Padua, Italy.
C M BarbagalloBiomedical Department of Internal Medicine and Specialistics, University of Palermo, Palermo, Italy.
P VerdecchiaHospital S. Maria della Misericordia, Perugia, Italy.
S MasiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
F MallamaciReggio Cal Unit, CNR-IFC, Clinical Epidemiology of Renal Diseases and Hypertension, Reggio Calabria, Italy.
M CirilloDepartment of Public Health, "Federico II" University of Naples, Naples, Italy.
M RattazziDepartment of Medicine, University of Padua, Padua, Italy.
P PaulettoMedicina Interna I, Ca' Foncello University Hospital, Treviso, Italy.
P CirilloNephrology, Dialysis and Transplantation Unit, Department of Emergency and Organ Transplantation, "Aldo Moro" University of Bari, Bari, Italy.
L GesualdoNephrology, Dialysis and Transplantation Unit, Department of Emergency and Organ Transplantation, "Aldo Moro" University of Bari, Bari, Italy.
A MazzaDepartment of Internal Medicine, Santa Maria della Misericordia General Hospital, AULSS 5 Polesana, Rovigo, Italy.
M VolpeDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University of Rome Sapienza, Sant'Andrea Hospital, Rome, Italy.
G TocciDivision of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University of Rome Sapienza, Sant'Andrea Hospital, Rome, Italy.
G IaccarinoDepartment of Advanced Biomedical Sciences, "Federico II" University of Naples, Naples, Italy.
P NazzaroDepartment of Medical Basic Sciences, Neurosciences and Sense Organs, University of Bari Medical School, Bari, Italy.
L LippaItalian Society of General Medicine (SIMG), Avezzano, L'Aquila, Italy.
G ParatiHealth Science Department, Milano-Bicocca University, Milan, Italy.
R Dell'OroHealth Science Department, Milano-Bicocca University, Milan, Italy.
F Quarti-TrevanoHealth Science Department, Milano-Bicocca University, Milan, Italy.
G GrassiHealth Science Department, Milano-Bicocca University, Milan, Italy.
A VirdisDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
C BorghiDepartment of Medical and Surgical Science, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension (SIIA)
University of Milano-Bicocca · ITUniversity of Bari Aldo Moro · ITUniversity of Brescia · ITUniversity of L'Aquila · ITUniversity of Padua · ITCa' Foncello Hospital · ITSapienza University of Rome · ITUniversity of Bologna · ITUniversity of Florence · ITUniversity of Genoa · ITUniversity of Pisa · ITAzienda Ospedaliera San Gerardo · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto di Fisiologia Clinica · ITOspedale Maggiore · ITOspedale Santa Maria della Misericordia di Rovigo · ITSocietà Italiana di Medicina Generale · ITUniversity of Naples Federico II · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The latest European Guidelines of Arterial Hypertension have officially introduced uric acid evaluation among the cardiovascular risk factors that should be evaluated in order to stratify patient's risk. In fact, it has been extensively evaluated and demonstrated to be an independent predictor not only of all-cause and cardiovascular mortality, but also of myocardial infraction, stroke and heart failure. Despite the large number of studies on this topic, an important open question that still need to be answered is the identification of a cardiovascular uric acid cut-off value. The actual hyperuricemia cut-off (> 6 mg/dL in women and 7 mg/dL in men) is principally based on the saturation point of uric acid but previous evidence suggests that the negative impact of cardiovascular system could occur also at lower levels. In this context, the Working Group on uric acid and CV risk of the Italian Society of Hypertension has designed the Uric acid Right for heArt Health project. The primary objective of this project is to define the level of uricemia above which the independent risk of CV disease may increase in a significantly manner. In this review we will summarize the first results obtained and describe the further planned analysis.

Indexed as

AdultAgedBiomarkersCardiovascular DiseasesFemaleHumansHyperuricemiaItalyMaleMiddle AgedMulticenter Studies as TopicObservational Studies as TopicPrognosisResearch DesignRetrospective StudiesRisk AssessmentBiomarkersUric AcidCardiovascular eventsCardiovascular mortalityUric acidURRAH

Identifiers

PMID32157643
OpenAlexW3012442527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.